| Literature DB >> 21152939 |
S-H Shi1, Yu Huang, S-J Cui, L-F Cheng, G-H Fu, X Li, Z Chen, C-X Peng, F Lin, J-S Lin, Jing-Liang Su.
Abstract
The complete sequence of an avian paramyxovirus type 1 (APMV-1) strain, FP1/02, isolated from Muscovy duck in China, was determined. Sequence analysis indicated that the complete genome of strain FP1/02 contained 15,192 nucleotides (nt), following the rule of six. The genome contained an extra 6-nt insertion in the non-coding region of the NP gene when compared with other APMV-1 strains, such as strains La Sota and Beaudette C. The cleavage site of the F protein was (112)R-R-Q-K-R↓F(117), indicating that the FP1/02 strain was virulent, but the morbidity and mortality varied with the species of duck. Genotypic analysis based on the F gene revealed that APMV-1 FP1/02 was a member of genotype VII. Phylogenetic analysis showed that the FP1/02 strain shared high identity with other APMV-1 strains such as ZJ1, SF02 and NA-1 isolated from geese.Entities:
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Year: 2010 PMID： 21152939 DOI： 10.1007/s00705-010-0866-y
Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574