Literature DB >> 21152565

Bead diffusion assay for discovering antimicrobial cyclic peptides.

Viviana S Fluxà1, Noélie Maillard, Malcolm G P Page, Jean-Louis Reymond.   

Abstract

A combinatorial library of 15,536 cyclic decapeptide analogues of tyrocidine A and gramicidin S was prepared on photocleavable TentaGel beads. The beads were photolyzed without solvent, and spread onto an agar plate inoculated with bacterial lawn. Clear zones were formed around beads carrying antimicrobially active peptides such as E18 c(kVOrnLfThiYOrnLq), which inhibited growth of B. subtilis and selected MRSA strains.

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Year:  2010        PMID： 21152565     DOI： 10.1039/c0cc04670a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

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Authors:  Wesley G Cochrane; Patrick R Fitzgerald; Brian M Paegel
Journal:  ACS Chem Biol       Date:  2021-11-20       Impact factor: 5.100

2.  Peptoid Library Agar Diffusion (PLAD) Assay for the High-Throughput Identification of Antimicrobial Peptoids.

Authors:  Kevin J Fisher; Jeremy A Turkett; Ashley E Corson; Kevin L Bicker
Journal:  ACS Comb Sci       Date:  2016-05-26       Impact factor: 3.784

3.  In Vitro Activity of the Novel Antimicrobial Peptide Dendrimer G3KL against Multidrug-Resistant Acinetobacter baumannii and Pseudomonas aeruginosa.

Authors:  João Pires; Thissa N Siriwardena; Michaela Stach; Regula Tinguely; Sara Kasraian; Francesco Luzzaro; Stephen L Leib; Tamis Darbre; Jean-Louis Reymond; Andrea Endimiani
Journal:  Antimicrob Agents Chemother       Date:  2015-10-12       Impact factor: 5.191

4.  Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms.

Authors:  Ivan Di Bonaventura; Xian Jin; Ricardo Visini; Daniel Probst; Sacha Javor; Bee-Ha Gan; Gaëlle Michaud; Antonino Natalello; Silvia Maria Doglia; Thilo Köhler; Christian van Delden; Achim Stocker; Tamis Darbre; Jean-Louis Reymond
Journal:  Chem Sci       Date:  2017-07-13       Impact factor: 9.825

5.  Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa.

Authors:  Runze He; Ivan Di Bonaventura; Ricardo Visini; Bee-Ha Gan; Yongchun Fu; Daniel Probst; Alexandre Lüscher; Thilo Köhler; Christian van Delden; Achim Stocker; Wenjing Hong; Tamis Darbre; Jean-Louis Reymond
Journal:  Chem Sci       Date:  2017-09-04       Impact factor: 9.825

6.  Development of a high-throughput strategy for discovery of potent analogues of antibiotic lysocin E.

Authors:  Hiroaki Itoh; Kotaro Tokumoto; Takuya Kaji; Atmika Paudel; Suresh Panthee; Hiroshi Hamamoto; Kazuhisa Sekimizu; Masayuki Inoue
Journal:  Nat Commun       Date:  2019-07-05       Impact factor: 14.919
  6 in total

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