Literature DB >> 21152461

IBD 2009: emerging research frontiers on the path to a cure.

A Hillary Steinhart1, G Tolomiczenko.   

Abstract

The Crohn's and Colitis Foundation of Canada (CCFC) hosted a research symposium in April 2009. The current article presents short synopses of the presentations given at that symposium. Invitees included CCFC-funded clinician-scientists and researchers, research administrators and international leaders in inflammatory bowel disease research. Research challenges were outlined while acknowledging advances made in several domains relevant to informing the search for cures. Following the scientific presentations, discussions endorsed current activities of the CCFC and supported the creation of a new pediatric inflammatory bowel disease initiative.

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Year:  2010        PMID: 21152461      PMCID: PMC2948766          DOI: 10.1155/2010/795780

Source DB:  PubMed          Journal:  Can J Gastroenterol        ISSN: 0835-7900            Impact factor:   3.522


  46 in total

1.  Distinct inflammatory mechanisms mediate early versus late colitis in mice.

Authors:  David M Spencer; Geertruida M Veldman; Subhashis Banerjee; Joseph Willis; Alan D Levine
Journal:  Gastroenterology       Date:  2002-01       Impact factor: 22.682

2.  Effects of mesalamine (5-aminosalicylic acid) on bacterial gene expression.

Authors:  Jaime Kaufman; Tanya A Griffiths; Michael G Surette; Susan Ness; Kevin P Rioux
Journal:  Inflamm Bowel Dis       Date:  2009-07       Impact factor: 5.325

3.  Panorganismal gut microbiome-host metabolic crosstalk.

Authors:  Francois-Pierre J Martin; Norbert Sprenger; Ivan K S Yap; Yulan Wang; Rodrigo Bibiloni; Florence Rochat; Serge Rezzi; Christine Cherbut; Sunil Kochhar; John C Lindon; Elaine Holmes; Jeremy K Nicholson
Journal:  J Proteome Res       Date:  2009-04       Impact factor: 4.466

4.  Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor.

Authors:  H Mashimo; D C Wu; D K Podolsky; M C Fishman
Journal:  Science       Date:  1996-10-11       Impact factor: 47.728

5.  IL-11, a pleiotropic cytokine: exciting new effects of IL-11 on gastrointestinal mucosal biology.

Authors:  J C Keith; L Albert; S T Sonis; C J Pfeiffer; R G Schaub
Journal:  Stem Cells       Date:  1994       Impact factor: 6.277

Review 6.  The role of the intestinal microbiota in enteric infection.

Authors:  Inna Sekirov; B Brett Finlay
Journal:  J Physiol       Date:  2009-06-02       Impact factor: 5.182

7.  Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study.

Authors:  Subra Kugathasan; Robert H Judd; Raymond G Hoffmann; Janice Heikenen; Gregorz Telega; Farhat Khan; Sally Weisdorf-Schindele; William San Pablo; Jean Perrault; Roger Park; Michael Yaffe; Christopher Brown; Maria T Rivera-Bennett; Issam Halabi; Alfonso Martinez; Ellen Blank; Steven L Werlin; Colin D Rudolph; David G Binion
Journal:  J Pediatr       Date:  2003-10       Impact factor: 4.406

8.  Polymorphisms in E-cadherin (CDH1) result in a mis-localised cytoplasmic protein that is associated with Crohn's disease.

Authors:  A M Muise; T D Walters; W K Glowacka; A M Griffiths; B-Y Ngan; H Lan; W Xu; M S Silverberg; D Rotin
Journal:  Gut       Date:  2009-04-26       Impact factor: 23.059

9.  Regulation of IL-11 expression in intestinal myofibroblasts: role of c-Jun AP-1- and MAPK-dependent pathways.

Authors:  Shigeki Bamba; Akira Andoh; Hirofumi Yasui; Jin Makino; Shokei Kim; Yoshihide Fujiyama
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2003-05-21       Impact factor: 4.052

10.  Functional expression of the interleukin-11 receptor alpha-chain and evidence of antiapoptotic effects in human colonic epithelial cells.

Authors:  Stephan Kiessling; Gerhard Muller-Newen; Sandra N Leeb; Martin Hausmann; Heiko C Rath; Jorn Strater; Tanja Spottl; Klaus Schlottmann; Johannes Grossmann; F A Montero-Julian; Jurgen Scholmerich; Tilo Andus; Armin Buschauer; Peter C Heinrich; Gerhard Rogler
Journal:  J Biol Chem       Date:  2003-12-29       Impact factor: 5.157

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