Literature DB >> 2114938

The gut mucosal barrier in bone marrow transplantation.

C Fegan1, C H Poynton, J A Whittaker.   

Abstract

The damage to the small bowel mucosal barrier was studied prospectively in 26 patients undergoing bone marrow transplantation. The conditioning regimens resulted in the small bowel mucosa becoming more permeable for up to 4 weeks. Acute graft-versus-host disease also compromised barrier function. There was no difference in gut damage between conditioning with chemotherapy only and chemoradiotherapy, but damage was greater in patients 30 years of age and above.

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Year:  1990        PMID: 2114938

Source DB:  PubMed          Journal:  Bone Marrow Transplant        ISSN: 0268-3369            Impact factor:   5.483


  13 in total

1.  Disturbance of purine nucleotide metabolism: a possible early key event in development of intestinal damage induced by chemotherapy.

Authors:  J E Johansson; B Soussi; U Bagge; T Ekman
Journal:  Dig Dis Sci       Date:  2001-02       Impact factor: 3.199

Review 2.  An official American Thoracic Society research statement: noninfectious lung injury after hematopoietic stem cell transplantation: idiopathic pneumonia syndrome.

Authors:  Angela Panoskaltsis-Mortari; Matthias Griese; David K Madtes; John A Belperio; Imad Y Haddad; Rodney J Folz; Kenneth R Cooke
Journal:  Am J Respir Crit Care Med       Date:  2011-05-01       Impact factor: 21.405

3.  LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantation.

Authors:  K R Cooke; A Gerbitz; J M Crawford; T Teshima; G R Hill; A Tesolin; D P Rossignol; J L Ferrara
Journal:  J Clin Invest       Date:  2001-06       Impact factor: 14.808

Review 4.  Translational research efforts in biomarkers and biology of early transplant-related complications.

Authors:  Sophie Paczesny; Maribel Diaz-Ricart; Enric Carreras; Enrique Carerras; Kenneth R Cooke
Journal:  Biol Blood Marrow Transplant       Date:  2011-01       Impact factor: 5.742

5.  Gastrointestinal and nutritional sequelae of bone marrow transplantation.

Authors:  A Papadopoulou; D R Lloyd; M D Williams; P J Darbyshire; I W Booth
Journal:  Arch Dis Child       Date:  1996-09       Impact factor: 3.791

6.  Intestinal permeability in patients with Crohn's disease and ulcerative colitis and their first degree relatives.

Authors:  P Munkholm; E Langholz; D Hollander; K Thornberg; M Orholm; K D Katz; V Binder
Journal:  Gut       Date:  1994-01       Impact factor: 23.059

Review 7.  The pathophysiology of acute graft-versus-host disease.

Authors:  James L M Ferrara; Kenneth R Cooke; Takanori Teshima
Journal:  Int J Hematol       Date:  2003-10       Impact factor: 2.490

8.  Gut toxicity during hemopoietic stem cell transplantation may predict acute graft-versus-host disease severity in patients.

Authors:  Jan-Erik Johansson; Tor Ekman
Journal:  Dig Dis Sci       Date:  2007-04-06       Impact factor: 3.199

9.  Antigenaemia during acute graft versus host disease.

Authors:  C Fegan; S K Jackson; J A Whittaker
Journal:  J Clin Pathol       Date:  1995-02       Impact factor: 3.411

10.  Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability.

Authors:  Sam C Nalle; Li Zuo; Ma Lora Drizella M Ong; Gurminder Singh; Alicia M Worthylake; Wangsun Choi; Mario Cabrero Manresa; Anna P Southworth; Karen L Edelblum; Gregory J Baker; Nora E Joseph; Peter A Savage; Jerrold R Turner
Journal:  J Clin Invest       Date:  2019-01-22       Impact factor: 19.456

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