Literature DB >> 21149366

Blast injuries to the lung: epidemiology and management.

Iain M J Mackenzie1, Bill Tunnicliffe.   

Abstract

Lung injury is frequently a component of the polytrauma sustained by military personnel surviving blast on the battlefield. This article describes a case series of the military casualties admitted to University Hospital Birmingham's critical care services (role 4 facility), during the period 1 July 2008 to 15 January 2010. Of the 135 casualties admitted, 107 (79.2%) were injured by explosive devices. Plain chest films taken soon after arrival in the role 4 facility were reviewed in 96 of the 107 patients. In 55 (57.3%) films a tracheal tube was present. One or more radiological abnormalities was present in 66 (68.75%) of the films. Five patients met the consensus criteria for the definition of adult respiratory distress syndrome (ARDS). The majority of casualties with blast-related lung injury were successfully managed with conventional ventilatory support employing a lung protective strategy; only a small minority received non-conventional support at any time in the form of high-frequency oscillatory ventilation. Of those casualties who survived to be received by the role 4 facility, none subsequently died as a consequence of lung injury.

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Year:  2011        PMID: 21149366      PMCID: PMC3013440          DOI: 10.1098/rstb.2010.0252

Source DB:  PubMed          Journal:  Philos Trans R Soc Lond B Biol Sci        ISSN: 0962-8436            Impact factor:   6.237


  16 in total

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  11 in total

1.  Proposed Iraq/Afghanistan War-Lung Injury (IAW-LI) Clinical Practice Recommendations: National Academy of Sciences' Institute of Medicine Burn Pits Workshop.

Authors:  Anthony Szema; Niely Mirsaidi; Bhumika Patel; Laura Viens; Edward Forsyth; Jonathan Li; Sophia Dang; Brittany Dukes; Jheison Giraldo; Preston Kim; Matthew Burns
Journal:  Am J Mens Health       Date:  2015-12-14

2.  Computational Modeling of Primary Blast Lung Injury: Implications for Ventilator Management.

Authors:  Jacob Herrmann; Merryn H Tawhai; David W Kaczka
Journal:  Mil Med       Date:  2019-03-01       Impact factor: 1.437

3.  Examining lethality risk for rodent studies of primary blast lung injury.

Authors:  William Brad Hubbard; Christina Hall; Venkata Siva Sai Suijith Sajja; Erink Lavik; Pamela VandeVord
Journal:  Biomed Sci Instrum       Date:  2014

4.  Development of an Animal Model for Burn-Blast Combined Injury and Cardiopulmonary System Changes in the Early Shock Stage.

Authors:  Quan Hu; Jiake Chai; Sen Hu; Jun Fan; Hong-Wei Wang; Li Ma; Hong-Jie Duan; Lingying Liu; Hongming Yang; Bai-Ling Li; Yi-He Wang
Journal:  Indian J Surg       Date:  2014-05-14       Impact factor: 0.656

Review 5.  Characterization of the response to primary blast injury.

Authors:  E Kirkman; S Watts
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2011-01-27       Impact factor: 6.237

6.  Local pulmonary administration of factor VIIa (rFVIIa) in diffuse alveolar hemorrhage (DAH) - a review of a new treatment paradigm.

Authors:  Lars Heslet; Jørn Dalsgaard Nielsen; Steen Nepper-Christensen
Journal:  Biologics       Date:  2012-03-06

7.  Hand grenade blast injuries in the Eastern Democratic Republic of Congo: a case series of 38 patients.

Authors:  Paul Munguakonkwa Budema; Romeo Bujiriri Murhega; Tshibambe Nathanael Tshimbombu; Georges Kuyigwa Toha; Fabrice Gulimwentuga Cikomola; Paterne Safari Mudekereza; Léon-Emmanuel Mubenga; Ghislain Maheshe Balemba; Darck Cubaka Badesire; Ulrick Sidney Kanmounye
Journal:  BMC Emerg Med       Date:  2022-03-19

8.  A Fatal Tyre Blast Injury: An Autopsy Case.

Authors:  Rajesh Kumar; Nishat Ahmed Sheikh
Journal:  Nepal J Epidemiol       Date:  2022-03-31

Review 9.  Understanding blast-induced neurotrauma: how far have we come?

Authors:  Ibolja Cernak
Journal:  Concussion       Date:  2017-06-08

Review 10.  Damage-Associated Molecular Patterns and Their Signaling Pathways in Primary Blast Lung Injury: New Research Progress and Future Directions.

Authors:  Ning Li; Chenhao Geng; Shike Hou; Haojun Fan; Yanhua Gong
Journal:  Int J Mol Sci       Date:  2020-08-31       Impact factor: 5.923

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