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Literature DB >> 21147945

The homocysteine hypothesis: still relevant to the prevention and treatment of cardiovascular disease?

Abstract

Although evidence suggests that the homocysteine hypothesis is still relevant as a predictor of cardiovascular risk, we cannot conclude that measuring the homocysteine level is useful in guiding treatment. Furthermore, studies of primary and secondary prevention show no evidence that taking folic acid or other B vitamins lowers the risk of cardiovascular events.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2010 PMID： 21147945 DOI： 10.3949/ccjm.77a.10036

Source DB: PubMed Journal: Cleve Clin J Med ISSN： 0891-1150 Impact factor: 2.321

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Cited

17 in total

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3. Anethole dithiolethione lowers the homocysteine and raises the glutathione levels in solid tissues and plasma of rats: a novel non-vitamin homocysteine-lowering agent.

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4. Lipoprotein(a) and homocysteine as genetic risk factors for vascular and neuropathic diabetic foot in type 2 diabetes mellitus.

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5. The relationship between the concentration of plasma homocysteine and chronic kidney disease: a cross sectional study of a large cohort.

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7. The association between obesity, cardiometabolic disease biomarkers, and innate immunity-related inflammation in Canadian adults.

Authors: Laura A Da Costa; Paul Arora; Bibiana García-Bailo; Mohamed Karmali; Ahmed El-Sohemy; Alaa Badawi
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