Literature DB >> 21147631

Lung mass in a 28-year-old male: a case report of a rare tumor.

Robert M Mroz1, M Korniluk, E Swidzinska, J Dzieciol, J Czaban, B Panek, E Chyczewska.   

Abstract

A twenty eight-year-old male presented with a two week history of dyspnea, cough, hemoptysis, chest pain, and fever 38-39°C. He also complained of loss of appetite, general weakness and left leg pain for two months preceding admission. He was referred with suspicion of lung tumor to our institution. Chest X-ray showed almost total atelectasis of the right lung with compensatory overinflation of the contralateral lung. Using computed tomography (CT), a lesion of diameter of 19.3 x 14.1 x 19.1 cm in the right lung, pleuritis, Th3 osteolysis, and compensatory overinflation of the left lung was seen. Bronchoscopy revealed a total obstruction of the right main bronchus due to submucosal infiltration and compression of the right main bronchus with negative histology of bronchial biopsy specimens. Transthoracic fine needle aspiration revealed celullae suspectae probabiliter neoplasmaticae suggesting tumor fusocellularis. USG of the abdomen revealed liver with numerous heterogeneous, solid areas hypo- and hyperechogenic, some of them with features of liquid or the disintegration up to diameter of 74 mm. Subsequent fine needle aspirations of the thorax and liver revealed fibrolamellar hepatocarcinoma and carcinoma adenoides of the lung. Patient underwent chemotherapy with 5-FU/DDP/VCR with no response. This report presents a case of a rare lung metastasis from FL-HCC.

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Year:  2010        PMID: 21147631      PMCID: PMC4360372          DOI: 10.1186/2047-783x-15-s2-95

Source DB:  PubMed          Journal:  Eur J Med Res        ISSN: 0949-2321            Impact factor:   2.175


  11 in total

1.  Treatment of fibrolamellar hepatoma with subtotal hepatectomy or transplantation.

Authors:  A D Pinna; S Iwatsuki; R G Lee; S Todo; J R Madariaga; J W Marsh; A Casavilla; I Dvorchik; J J Fung; T E Starzl
Journal:  Hepatology       Date:  1997-10       Impact factor: 17.425

Review 2.  Fibrolamellar hepatocellular carcinoma.

Authors:  Shu Liu; Kwok Wah Chan; Bingyuan Wang; Liang Qiao
Journal:  Am J Gastroenterol       Date:  2009-07-28       Impact factor: 10.864

3.  Clinicopathologic features and survival in fibrolamellar carcinoma: comparison with conventional hepatocellular carcinoma with and without cirrhosis.

Authors:  Sanjay Kakar; Lawrence J Burgart; Kenneth P Batts; Joaquin Garcia; Dhanpat Jain; Linda D Ferrell
Journal:  Mod Pathol       Date:  2005-11       Impact factor: 7.842

Review 4.  Natural history of hepatocellular carcinoma including fibrolamellar and hepato-cholangiocarcinoma variants.

Authors:  Kunio Okuda
Journal:  J Gastroenterol Hepatol       Date:  2002-04       Impact factor: 4.029

5.  Clinical features of hepatocellular carcinoma with extrahepatic metastases.

Authors:  Mitsuteru Natsuizaka; Takumi Omura; Toru Akaike; Yasuaki Kuwata; Katsu Yamazaki; Takahiro Sato; Yoshiyasu Karino; Jouji Toyota; Toshihiro Suga; Masahiro Asaka
Journal:  J Gastroenterol Hepatol       Date:  2005-11       Impact factor: 4.029

6.  Clinical features and prognosis of patients with extrahepatic metastases from hepatocellular carcinoma.

Authors:  Kiminori Uka; Hiroshi Aikata; Shintaro Takaki; Hiroo Shirakawa; Soo-Cheol Jeong; Keitaro Yamashina; Akira Hiramatsu; Hideaki Kodama; Shoichi Takahashi; Kazuaki Chayama
Journal:  World J Gastroenterol       Date:  2007-01-21       Impact factor: 5.742

7.  Extrahepatic spread from hepatocellular carcinoma: who are candidates for aggressive anti-cancer treatment?

Authors:  Hiroshi Ishii; Junji Furuse; Taira Kinoshita; Masaru Konishi; Toshio Nakagohri; Shinichiro Takahashi; Naoto Gotohda; Kouhei Nakachi; Masahiro Yoshino
Journal:  Jpn J Clin Oncol       Date:  2004-12       Impact factor: 3.019

8.  Fibrolamellar carcinoma of the liver: a tumor of adolescents and young adults with distinctive clinico-pathologic features.

Authors:  J R Craig; R L Peters; H A Edmondson; M Omata
Journal:  Cancer       Date:  1980-07-15       Impact factor: 6.860

9.  Hepatocellular carcinoma: importance of histologic classification as a prognostic factor.

Authors:  W J Wood; M Rawlings; H Evans; C N Lim
Journal:  Am J Surg       Date:  1988-05       Impact factor: 2.565

10.  Is histological diagnosis of primary liver carcinomas with fibrous stroma reproducible among experts?

Authors:  G Malouf; B Falissard; D Azoulay; F Callea; L D Ferrell; Z D Goodman; Y Hayashi; H-C Hsu; S G Hubscher; M Kojiro; I O Ng; A C Paterson; M Reynes; E-S Zafrani; J-F Emile
Journal:  J Clin Pathol       Date:  2009-01-20       Impact factor: 3.411

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  1 in total

1.  Clinical features and surgical outcomes of fibrolamellar hepatocellular carcinoma: retrospective analysis of a single-center experience.

Authors:  Anastasia Lemekhova; Daniel Hornuss; Georgios Polychronidis; Philipp Mayer; Christian Rupp; Thomas Longerich; Karl-Heinz Weiss; Markus Büchler; Arianeb Mehrabi; Katrin Hoffmann
Journal:  World J Surg Oncol       Date:  2020-05-12       Impact factor: 2.754

  1 in total

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