Malakoplakia of the pancreas.

We report a case of malakoplakia arising in the pancreas of a 45-year-old woman. Clinical and histological features are described. Malakoplakia was present with chronic pancreatitis and adenocarcinoma. The aetiology of malakoplakia at this site may be due to a stromal response to carcinoma or an abnormal localised histiocytic response to infection or inflammation. This case and previous reported cases suggest that the aetiology and pathogenesis of pancreatic malakoplakia is not the same for all patients.