Literature DB >> 21145494

Another tier for caspase regulation: IAPs as NEDD8 E3 ligases.

Sigi Benjamin1, Hermann Steller.   

Abstract

Many inhibitor of apoptosis proteins (IAPs) function as E3 ligases to ubiquitinate important cell death proteins, including caspases. Broemer et al. (2010) report recently in Molecular Cell that IAPs can also inhibit caspases by promoting conjugation of the UBL NEDD8.
Copyright © 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID： 21145494      PMCID： PMC3022555          DOI： 10.1016/j.devcel.2010.11.014

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  10 in total

Review 1.  The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction.

Authors:  Michael H Glickman; Aaron Ciechanover
Journal:  Physiol Rev       Date:  2002-04       Impact factor: 37.312

Review 2.  IAP proteins: blocking the road to death's door.

Authors:  Guy S Salvesen; Colin S Duckett
Journal:  Nat Rev Mol Cell Biol       Date:  2002-06       Impact factor: 94.444

Review 3.  Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes.

Authors:  Francisca E Reyes-Turcu; Karen H Ventii; Keith D Wilkinson
Journal:  Annu Rev Biochem       Date:  2009       Impact factor: 23.643

Review 4.  Caspases: enemies within.

Authors:  N A Thornberry; Y Lazebnik
Journal:  Science       Date:  1998-08-28       Impact factor: 47.728

5.  Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation.

Authors:  June-Tai Wu; Hsiu-Chen Lin; Yen-Chen Hu; Cheng-Ting Chien
Journal:  Nat Cell Biol       Date:  2005-08-28       Impact factor: 28.824

Review 6.  Regulation of cell death by the ubiquitin-proteasome system.

Authors:  Maya Bader; Hermann Steller
Journal:  Curr Opin Cell Biol       Date:  2009-10-21       Impact factor: 8.382

Review 7.  Regulation of apoptosis in Drosophila.

Authors:  H Steller
Journal:  Cell Death Differ       Date:  2008-04-25       Impact factor: 15.828

8.  NUB1 promotes cytoplasmic localization of p53 through cooperation of the NEDD8 and ubiquitin pathways.

Authors:  G Liu; D P Xirodimas
Journal:  Oncogene       Date:  2010-01-25       Impact factor: 9.867

9.  Systematic in vivo RNAi analysis identifies IAPs as NEDD8-E3 ligases.

Authors:  Meike Broemer; Tencho Tenev; Kristoffer T G Rigbolt; Sophie Hempel; Blagoy Blagoev; John Silke; Mark Ditzel; Pascal Meier
Journal:  Mol Cell       Date:  2010-12-10       Impact factor: 17.970

10.  Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.

Authors:  David M Duda; Laura A Borg; Daniel C Scott; Harold W Hunt; Michal Hammel; Brenda A Schulman
Journal:  Cell       Date:  2008-09-19       Impact factor: 41.582
  10 in total
  3 in total

1.  Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system.

Authors:  Rajesh K Singh; Sylvia Zerath; Oded Kleifeld; Martin Scheffner; Michael H Glickman; David Fushman
Journal:  Mol Cell Proteomics       Date:  2012-10-26       Impact factor: 5.911

Review 2.  Neddylation dysfunction in Alzheimer's disease.

Authors:  Yuzhi Chen; Rachael L Neve; Helena Liu
Journal:  J Cell Mol Med       Date:  2012-11       Impact factor: 5.310

3.  Targeting inhibitors of apoptosis proteins suppresses medulloblastoma cell proliferation via G2/M phase arrest and attenuated neddylation of p21.

Authors:  Shu-Mei Chen; Tzu-Kang Lin; Yuan-Yun Tseng; Chiao-Hui Tu; Tai-Ngar Lui; Shiang-Fu Huang; Ling-Ling Hsieh; Ying-Ying Li
Journal:  Cancer Med       Date:  2018-07-09       Impact factor: 4.452
  3 in total

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