| Literature DB >> 21145478 |
Alfredo Gimenez-Cassina1, Nika N Danial.
Abstract
The BCL-2 family member Noxa induces apoptosis by antagonizing the prosurvival protein MCL-1. In this issue of Molecular Cell, Lowman et al. (2010) uncover a glucose-dependent phosphoregulatory mechanism that inactivates Noxa's apoptotic function and triggers its capacity to modulate glucose metabolism.Entities:
Year: 2010 PMID: 21145478 DOI: 10.1016/j.molcel.2010.11.037
Source DB: PubMed Journal: Mol Cell ISSN: 1097-2765 Impact factor: 17.970