Literature DB >> 2114537

Activity of DMBA, DMH and CP in triple- and single-dose rodent bone-marrow micronucleus assays.

H Tinwell1, L Bandara, J Ashby.   

Abstract

1,2-Dimethylhydrazine, 7,12-dimethylbenzanthracene and cyclophosphamide were detected as positive using the triple-dose test protocol described by MacGregor (1989). Determination of the 3 day MLD may complicate the use of this test protocol.

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Year:  1990        PMID： 2114537     DOI： 10.1016/0165-1161(90)90015-g

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  2 in total

Review 1.  Comparative activity of human carcinogens and NTP rodent carcinogens in the mouse bone marrow micronucleus assay: an integrative approach to genetic toxicity data assessment.

Authors:  H Tinwell; J Ashby
Journal:  Environ Health Perspect       Date:  1994-09       Impact factor: 9.031

2.  Arsenite as the probable active species in the human carcinogenicity of arsenic: mouse micronucleus assays on Na and K arsenite, orpiment, and Fowler's solution.

Authors:  H Tinwell; S C Stephens; J Ashby
Journal:  Environ Health Perspect       Date:  1991-11       Impact factor: 9.031
  2 in total

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