Literature DB >> 21145069

Cardioscopy-guided surgery: intracardiac mitral and tricuspid valve repair under direct visualization in the beating heart.

Akira Shiose1, Tohru Takaseya, Hideyuki Fumoto, Tetsuya Horai, Hyun-Il Kim, Kiyotaka Fukamachi, Tomislav Mihaljevic.   

Abstract

OBJECTIVE: Cardioscopy is a novel imaging method that allows closed-chest, real-time fiberoptic imaging of intracardiac structures. This study tested the feasibility and safety of cardioscopy as a platform for mitral and tricuspid valve surgery in the beating heart.
METHODS: Through a median sternotomy, cardiopulmonary bypass was established in 10 calves. Lactated Ringer's solution was administered through the pulmonary artery to eliminate residual blood volumes in the lung vasculature and was drained through a left ventricular cannula. A fiberoptic cardioscope within its translucent outer sheath was inserted through the left ventricle. Irrigating solution was continuously administered through the cardioscope sheath for clearer visualization. An endoscopic clip was used for edge-to-edge repair of the mitral and tricuspid valves. After mitral valve clipping, the cardioscope was inserted into the right ventricle. The solution was administered from the right atrium and continuously drained from the pulmonary artery. After tricuspid valve repair, the animal was weaned from cardiopulmonary bypass.
RESULTS: Successful double-valve repair was carried out in all 10 cases. All calves were weaned from cardiopulmonary bypass with dobutamine only. Hematocrit values were maintained during the procedure (pre 29.0% ± 3.1% vs post 28.5% ± 3.6%, P = .70).
CONCLUSIONS: This study showed the technical feasibility of beating heart valve surgery using direct cardioscopic visualization. Cardioscopy represents a promising platform for future interventions and surgery under direct visualization in the beating heart.
Copyright © 2011 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

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Year:  2010        PMID: 21145069     DOI: 10.1016/j.jtcvs.2010.09.053

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  3 in total

1.  New Cardioscope-Based Platform for Minimally Invasive and Percutaneous Beating Heart Interventions.

Authors:  Jamshid H Karimov; Tomislav Mihaljevic; Shengqiang Gao; Gengo Sunagawa; Patrick Grady; Martin Sinkewich; Kiyotaka Fukamachi
Journal:  Semin Thorac Cardiovasc Surg       Date:  2018-10-10

2.  Optically-guided instrument for transapical beating-heart delivery of artificial mitral chordae tendineae.

Authors:  Zurab Machaidze; Margherita Mencattelli; Gustavo Arnal; Karl Price; Fei-Yi Wu; Viktoria Weixler; David W Brown; John E Mayer; Pierre E Dupont
Journal:  J Thorac Cardiovasc Surg       Date:  2019-03-21       Impact factor: 5.209

3.  Creation of nonischemic functional mitral regurgitation by annular dilatation and nonplanar modification in a chronic in vivo swine model.

Authors:  Haruo Yamauchi; Eric N Feins; Nikolay V Vasilyev; Shogo Shimada; David Zurakowski; Pedro J Del Nido
Journal:  Circulation       Date:  2013-09-10       Impact factor: 29.690

  3 in total

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