Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Asymmetric synthesis of tertiary benzylic alcohols.

Literature DB >> 21142190

Asymmetric synthesis of tertiary benzylic alcohols.

Monika I Antczak¹, Feng Cai, Joseph M Ready.

Abstract

Vinyl, aryl, and alkynyl organometallics add to ketones containing a stereogenic sulfoxide. Tertiary alcohols are generated in diastereomerically and enantiomerically pure form. Reductive lithiation converts the sulfoxide into a variety of useful functional groups.

Entities: Chemical Disease Gene

Mesh：

Substances：

Year: 2010 PMID： 21142190 PMCID： PMC3028934 DOI： 10.1021/ol102567h

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

20 in total

1. Development of bifunctional salen catalysts: rapid, chemoselective alkylations of alpha-ketoesters.

Authors: Erin F DiMauro; Marisa C Kozlowski
Journal: J Am Chem Soc Date: 2002-10-30 Impact factor: 15.419

2. Full chirality transfer in the conversion of secondary alcohols into tertiary boronic esters and alcohols using lithiation-borylation reactions.

Authors: Viktor Bagutski; Rosalind M French; Varinder K Aggarwal
Journal: Angew Chem Int Ed Engl Date: 2010-07-12 Impact factor: 15.336

3. Highly active chiral phosphoramide-Zn(II) complexes as conjugate acid-base catalysts for enantioselective organozinc addition to ketones.

Authors: Manabu Hatano; Takashi Miyamoto; Kazuaki Ishihara
Journal: Org Lett Date: 2007-09-29 Impact factor: 6.005

4. Catalytic asymmetric alkylation of aldehydes with grignard reagents.

Authors: Yusuke Muramatsu; Toshiro Harada
Journal: Angew Chem Int Ed Engl Date: 2008 Impact factor: 15.336

Review 5. Catalytic asymmetric organozinc additions to carbonyl compounds.

Authors: L Pu; H B Yu
Journal: Chem Rev Date: 2001-03 Impact factor: 60.622

6. Catalytic asymmetric addition of alkylzinc and functionalized alkylzinc reagents to ketones.

Authors: Sang-Jin Jeon; Hongmei Li; Celina García; Lynne K LaRochelle; Patrick J Walsh
Journal: J Org Chem Date: 2005-01-21 Impact factor: 4.354

7. Highly enantioselective phenylacetylene additions to ketones catalyzed by (S)-BINOL-Ti complex.

Authors: Yifeng Zhou; Rui Wang; Zhaoqing Xu; Wenjin Yan; Lei Liu; Yongfeng Kang; Zhijian Han
Journal: Org Lett Date: 2004-11-11 Impact factor: 6.005

8. Highly enantioselective alkynylation of alpha-keto ester: an efficient method for constructing a chiral tertiary carbon center.

Authors: Biao Jiang; Zili Chen; Xiaoxia Tang
Journal: Org Lett Date: 2002-10-03 Impact factor: 6.005

9. Remote stereocontrol mediated by a sulfinyl group: synthesis of allylic alcohols via chemoselective and diastereoselective reduction of gamma-methylene delta-ketosulfoxides.

Authors: José L García Ruano; M Angeles Fernández-Ibáñez; José A Fernández-Salas; M Carmen Maestro; Pablo Márquez-López; M Mercedes Rodríguez-Fernández
Journal: J Org Chem Date: 2009-02-06 Impact factor: 4.354