| Literature DB >> 21141809 |
Yun Zhang1, Timothy F Jamison, Sejal Patel, Nello Mainolfi.
Abstract
A convenient and efficient flow method for Ullmann condensations, Sonogashira couplings, and decarboxylation reactions using a commercially available copper tube flow reactor (CTFR) is described. The heated CTFR effects these transformations without added metals (e.g., Pd), ligands, or reagents, and in greater than 90% yield in most cases examined.Entities:
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Year: 2010 PMID： 21141809 DOI： 10.1021/ol1026848
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005