Literature DB >> 21136126

Temperament profiles, 5-HT2A genotype, and response to treatment with SSRIs in major depression.

Kadri Andre1, Olli Kampman, Eija Setälä-Soikkeli, Merja Viikki, Outi Poutanen, Timo Nuolivirta, Nina Mononen, Terho Lehtimäki, Esa Leinonen, Ari Illi.   

Abstract

Variation in antidepressive medication response according to 5-HT2A genotype has been reported in several studies. Temperament has been proposed to be one of the vulnerability factors in mood and anxiety disorders. We studied temperament profiles of 98 patients with major depression and explored the interaction between Temperament and Character Inventory (TCI) temperament dimensions, 5-HT2A genotype (SNPs rs6311, rs6313 and rs7997012) and treatment response. No interactive effects for TCI temperament dimensions and 5-HT2A genotypes on antidepressive treatment response were found.

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Year:  2010        PMID： 21136126     DOI： 10.1007/s00702-010-0512-6

Source DB:  PubMed          Journal:  J Neural Transm (Vienna)        ISSN： 0300-9564            Impact factor:   3.575


  16 in total

1.  [Polymorphism of the serotonin 2A receptor gene (5HTR2A) and personality traits].

Authors:  V E Golimbet; M V Alfimova; N G Mitiushina
Journal:  Mol Biol (Mosk)       Date:  2004 May-Jun

2.  Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort.

Authors:  Silvia Paddock; Gonzalo Laje; Dennis Charney; A John Rush; Alexander F Wilson; Alexa J M Sorant; Robert Lipsky; Stephen R Wisniewski; Husseini Manji; Francis J McMahon
Journal:  Am J Psychiatry       Date:  2007-08       Impact factor: 18.112

3.  Medial prefrontal cortex 5-HT(2A) density is correlated with amygdala reactivity, response habituation, and functional coupling.

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Journal:  Cereb Cortex       Date:  2009-03-25       Impact factor: 5.357

4.  Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients.

Authors:  Masaki Kato; Tsuyoshi Fukuda; Masataka Wakeno; Kazuhiro Fukuda; Gaku Okugawa; Yuka Ikenaga; Megumi Yamashita; Yoshiteru Takekita; Kenji Nobuhara; Junichi Azuma; Toshihiko Kinoshita
Journal:  Neuropsychobiology       Date:  2006-07-26       Impact factor: 2.328

5.  Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment.

Authors:  Francis J McMahon; Silvia Buervenich; Dennis Charney; Robert Lipsky; A John Rush; Alexander F Wilson; Alexa J M Sorant; George J Papanicolaou; Gonzalo Laje; Maurizio Fava; Madhukar H Trivedi; Stephen R Wisniewski; Husseini Manji
Journal:  Am J Hum Genet       Date:  2006-03-20       Impact factor: 11.025

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Authors:  P W Burnet; S L Eastwood; K Lacey; P J Harrison
Journal:  Brain Res       Date:  1995-04-03       Impact factor: 3.252

Review 7.  A psychobiological model of temperament and character.

Authors:  C R Cloninger; D M Svrakic; T R Przybeck
Journal:  Arch Gen Psychiatry       Date:  1993-12

8.  The serotonin receptor 2A gene moderates the influence of parental socioeconomic status on adulthood harm avoidance.

Authors:  Markus Jokela; Terho Lehtimäki; Liisa Keltikangas-Järvinen
Journal:  Behav Genet       Date:  2007-05-09       Impact factor: 2.805

9.  A new depression scale designed to be sensitive to change.

Authors:  S A Montgomery; M Asberg
Journal:  Br J Psychiatry       Date:  1979-04       Impact factor: 9.319

10.  5-HT2A SNPs and the Temperament and Character Inventory.

Authors:  Alessandro Serretti; Raffaella Calati; Ina Giegling; Annette M Hartmann; Hans-Jürgen Möller; Cristina Colombo; Dan Rujescu
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2007-05-26       Impact factor: 5.067
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  2 in total

1.  Association between serotonin cumulative genetic score and the Behavioral Approach System (BAS): Moderation by early life environment.

Authors:  Rahel Pearson; John E McGeary; Christopher G Beevers
Journal:  Pers Individ Dif       Date:  2014-11-01

2.  5-HTR1A and 5-HTR2A genetic polymorphisms and SSRI antidepressant response in depressive Chinese patients.

Authors:  Zai-Quan Dong; Xi-Rong Li; Lin He; Guang He; Tao Yu; Xue-Li Sun
Journal:  Neuropsychiatr Dis Treat       Date:  2016-07-04       Impact factor: 2.570
  2 in total

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