Literature DB >> 21134396

Chitosan and its derivatives for gene delivery.

N Saranya1, A Moorthi, S Saravanan, M Pandima Devi, N Selvamurugan.   

Abstract

Gene delivery can particularly be used for the treatment of diseases by the insertion of genetic materials (DNA and RNA) into mammalian cells either to express new proteins or to prevent the expression of existing proteins. Chitosan, a natural polymer is nontoxic, biocompatible, and biodegradable and it is used as a support material for gene delivery. However, practical use of chitosan has been mainly limited to its unmodified forms, and thus modified chitosans can be used for the wide range of biomedical applications including the interaction and intracellular delivery of genetic materials. In this context, this review paper provides the recent development on chitosan derivatives available for gene delivery.
Copyright © 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID： 21134396     DOI： 10.1016/j.ijbiomac.2010.11.013

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN： 0141-8130            Impact factor:   6.953


  24 in total

1.  Chitosan-based nanoparticles as a sustained protein release carrier for tissue engineering applications.

Authors:  Yaping Hou; Junli Hu; Hyejin Park; Min Lee
Journal:  J Biomed Mater Res A       Date:  2012-01-24       Impact factor: 4.396

2.  Development of antibody-modified chitosan nanoparticles for the targeted delivery of siRNA across the blood-brain barrier as a strategy for inhibiting HIV replication in astrocytes.

Authors:  Jijin Gu; Karam Al-Bayati; Emmanuel A Ho
Journal:  Drug Deliv Transl Res       Date:  2017-08       Impact factor: 4.617

3.  Recent advances in nonviral vectors for gene delivery.

Authors:  Xia Guo; Leaf Huang
Journal:  Acc Chem Res       Date:  2011-08-26       Impact factor: 22.384

4.  Therapeutic efficiency of folated poly(ethylene glycol)-chitosan-graft-polyethylenimine-Pdcd4 complexes in H-ras12V mice with liver cancer.

Authors:  You-Kyoung Kim; Arash Minai-Tehrani; Jae-Ho Lee; Chong-Su Cho; Myung-Haing Cho; Hu-Lin Jiang
Journal:  Int J Nanomedicine       Date:  2013-04-16

5.  Triggered rapid degradation of nanoparticles for gene delivery.

Authors:  José M Morachis; Enas A Mahmoud; Jagadis Sankaranarayanan; Adah Almutairi
Journal:  J Drug Deliv       Date:  2012-06-19

6.  BMP2 gene delivery to bone mesenchymal stem cell by chitosan-g-PEI nonviral vector.

Authors:  Jianhui Yue; Jun Wu; Di Liu; Xiaoli Zhao; William W Lu
Journal:  Nanoscale Res Lett       Date:  2015-04-29       Impact factor: 4.703

7.  Anti-epidermal growth factor receptor siRNA carried by chitosan-transacylated lipid nanocapsules increases sensitivity of glioblastoma cells to temozolomide.

Authors:  Khaled Messaoudi; Patrick Saulnier; Kim Boesen; Jean-Pierre Benoit; Frederic Lagarce
Journal:  Int J Nanomedicine       Date:  2014-03-24

8.  Inorganic Nanomaterial-Mediated Gene Therapy in Combination with Other Antitumor Treatment Modalities.

Authors:  Guanyou Lin; Richard A Revia; Miqin Zhang
Journal:  Adv Funct Mater       Date:  2020-10-13       Impact factor: 18.808

9.  Transporting antitumor drug tamoxifen and its metabolites, 4-hydroxytamoxifen and endoxifen by chitosan nanoparticles.

Authors:  Daniel Agudelo; Sriwanna Sanyakamdhorn; Shoherh Nafisi; Heidar-Ali Tajmir-Riahi
Journal:  PLoS One       Date:  2013-03-20       Impact factor: 3.240

Review 10.  Chitin, chitosan, and glycated chitosan regulate immune responses: the novel adjuvants for cancer vaccine.

Authors:  Xiaosong Li; Min Min; Nan Du; Ying Gu; Tomas Hode; Mark Naylor; Dianjun Chen; Robert E Nordquist; Wei R Chen
Journal:  Clin Dev Immunol       Date:  2013-03-04
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