Literature DB >> 21132828

An NMR spectroscopic method to identify and classify thiol-trapping agents: revival of Michael acceptors for drug discovery?

Cristina Avonto1, Orazio Taglialatela-Scafati, Federica Pollastro, Alberto Minassi, Vincenzo Di Marzo, Luciano De Petrocellis, Giovanni Appendino.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21132828     DOI： 10.1002/anie.201005959

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


× No keyword cloud information.
  39 in total

1.  Effect of sesquiterpene lactone coronopilin on leukaemia cell population growth, cell type-specific induction of apoptosis and mitotic catastrophe.

Authors:  R Cotugno; R Fortunato; A Santoro; D Gallotta; A Braca; N De Tommasi; M A Belisario
Journal:  Cell Prolif       Date:  2011-12-14       Impact factor: 6.831

2.  Design and synthesis of novel antimicrobials with activity against Gram-positive bacteria and mycobacterial species, including M. tuberculosis.

Authors:  V V N Phani Babu Tiruveedhula; Christopher M Witzigmann; Ranjit Verma; M Shahjahan Kabir; Marc Rott; William R Schwan; Sara Medina-Bielski; Michelle Lane; William Close; Rebecca L Polanowski; David Sherman; Aaron Monte; Jeffrey R Deschamps; James M Cook
Journal:  Bioorg Med Chem       Date:  2013-10-21       Impact factor: 3.641

3.  The Daniel K. Inouye College of Pharmacy Scripts: Poha Berry (Physalis peruviana) with Potential Anti-inflammatory and Cancer Prevention Activities.

Authors:  Leng Chee Chang; Mayuramas Sang-Ngern; John M Pezzuto; Carolyn Ma
Journal:  Hawaii J Med Public Health       Date:  2016-11

4.  Elucidating the Catalytic Power of Glutamate Racemase by Investigating a Series of Covalent Inhibitors.

Authors:  Nicholas R Vance; Katie R Witkin; Patrick W Rooney; Yalan Li; Marshall Pope; M Ashley Spies
Journal:  ChemMedChem       Date:  2018-11-21       Impact factor: 3.466

Review 5.  Counting on natural products for drug design.

Authors:  Tiago Rodrigues; Daniel Reker; Petra Schneider; Gisbert Schneider
Journal:  Nat Chem       Date:  2016-04-25       Impact factor: 24.427

6.  The anti-migraine component of butterbur extracts, isopetasin, desensitizes peptidergic nociceptors by acting on TRPA1 cation channel.

Authors:  Silvia Benemei; Francesco De Logu; Simone Li Puma; Ilaria Maddalena Marone; Elisabetta Coppi; Filippo Ugolini; Wolfgang Liedtke; Federica Pollastro; Giovanni Appendino; Pierangelo Geppetti; Serena Materazzi; Romina Nassini
Journal:  Br J Pharmacol       Date:  2017-07-20       Impact factor: 8.739

7.  Umbellulone modulates TRP channels.

Authors:  Jian Zhong; Alberto Minassi; Jean Prenen; Orazio Taglialatela-Scafati; Giovanni Appendino; Bernd Nilius
Journal:  Pflugers Arch       Date:  2011-10-29       Impact factor: 3.657

8.  Synthesis of 15-methylene-eburnamonine from (+)-vincamine, evaluation of anticancer activity, and investigation of mechanism of action by quantitative NMR.

Authors:  James R Woods; Mark V Riofski; Mary M Zheng; Melissa A O'Banion; Huaping Mo; Julia Kirshner; David A Colby
Journal:  Bioorg Med Chem Lett       Date:  2013-09-06       Impact factor: 2.823

9.  Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with down-regulation and covalent binding at cysteine 303 of β-tubulin.

Authors:  Marie L Antony; Joomin Lee; Eun-Ryeong Hahm; Su-Hyeong Kim; Adam I Marcus; Vandana Kumari; Xinhua Ji; Zhen Yang; Courtney L Vowell; Peter Wipf; Guy T Uechi; Nathan A Yates; Guillermo Romero; Saumendra N Sarkar; Shivendra V Singh
Journal:  J Biol Chem       Date:  2013-12-02       Impact factor: 5.157

10.  Hirsutinolide Series Inhibit Stat3 Activity, Alter GCN1, MAP1B, Hsp105, G6PD, Vimentin, TrxR1, and Importin α-2 Expression, and Induce Antitumor Effects against Human Glioma.

Authors:  Gabriella Miklossy; Ui Joung Youn; Peibin Yue; Mingming Zhang; Chih-Hong Chen; Tyvette S Hilliard; David Paladino; Yifei Li; Justin Choi; Jann N Sarkaria; Joel K Kawakami; Supakit Wongwiwatthananukit; Yuan Chen; Dianqing Sun; Leng Chee Chang; James Turkson
Journal:  J Med Chem       Date:  2015-09-17       Impact factor: 7.446
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.