Literature DB >> 21132679

Khat a drug of abuse: roles of free radicals and antioxidants.

Samir L Aleryani1, Rowaida A Aleryani, Ahmed A Al-Akwa.   

Abstract

Many articles have reviewed the health impact of Khat consumption; however the role of free radicals in the pathogenesis associated with short- and long-term consumption of Khat is absent in the literature. As free radicals and antioxidants converge across various mechanisms in normal physiological function and in disease, this review attempts to uncover the role of endogenous free radicals and the mechanism of cellular injury associated with Khat consumption.
Copyright © 2010 John Wiley & Sons, Ltd.

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Year:  2010        PMID： 21132679     DOI： 10.1002/dta.224

Source DB:  PubMed          Journal:  Drug Test Anal        ISSN： 1942-7603            Impact factor:   3.345


  5 in total

Review 1.  Cognitive deficits and neurotoxicity induced by synthetic cathinones: is there a role for neuroinflammation?

Authors:  Jonna M Leyrer-Jackson; Erin K Nagy; M Foster Olive
Journal:  Psychopharmacology (Berl)       Date:  2018-10-27       Impact factor: 4.530

2.  Subchronic oral administration of crude khat extract (Catha edulis forsk) induces schizophernic-like symptoms in mice.

Authors:  Tegegne Bogale; Epherm Engidawork; Engida Yisma
Journal:  BMC Complement Altern Med       Date:  2016-05-31       Impact factor: 3.659

3.  Distinct single cell signal transduction signatures in leukocyte subsets stimulated with khat extract, amphetamine-like cathinone, cathine or norephedrine.

Authors:  Therese Bredholt; Elisabeth Ersvær; Bjarte Skoe Erikstein; André Sulen; Håkon Reikvam; Hans Jørgen Aarstad; Anne Christine Johannessen; Olav Karsten Vintermyr; Øystein Bruserud; Bjørn Tore Gjertsen
Journal:  BMC Pharmacol Toxicol       Date:  2013-07-11       Impact factor: 2.483

4.  Catha edulis Extract Induces H9c2 Cell Apoptosis by Increasing Reactive Oxygen Species Generation and Activation of Mitochondrial Proteins.

Authors:  Syam Mohan; Siddig Ibrahim Abdelwahab; Yahya Hasan Hobani; Suvitha Syam; Adel S Al-Zubairi; Rashad Al-Sanousi; Magbool Essa Oraiby
Journal:  Pharmacogn Mag       Date:  2016-05       Impact factor: 1.085

5.  Khat Induced Toxicity: Role on Its Modulating Effects on Inflammation and Oxidative Stability.

Authors:  Siddig Ibrahim Abdelwahab; Rashad Alsanosy; Manal Mohamed Elhassan Taha; Syam Mohan
Journal:  Biomed Res Int       Date:  2018-05-30       Impact factor: 3.411
  5 in total

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