Literature DB >> 21132166

Concise synthesis of catechin probes enabling analysis and imaging of EGCg.

Atsushi Yoshida1, Yasuo Hirooka, Yusuke Sugata, Mariko Nitta, Tamiko Manabe, Shunsuke Ido, Kouki Murakami, Repon Kumer Saha, Takashi Suzuki, Motohiro Ohshima, Akira Yoshida, Kunihiko Itoh, Kosuke Shimizu, Naoto Oku, Takumi Furuta, Tomohiro Asakawa, Toshiyuki Wakimoto, Toshiyuki Kan.   

Abstract

A concise synthesis of APDOEGCg (3) was accomplished. Due to the reactivity of its amine group, the compound could be easily converted to the fluorescein probe 21 and immunogen probe 22 efficiently. We then demonstrated the usefulness of the probes for imaging studies and the generation of antibodies.

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Year:  2010        PMID: 21132166     DOI: 10.1039/c0cc03676e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  5 in total

1.  Synthesis and structure-activity relationships of EGCG analogues, a recently identified Hsp90 inhibitor.

Authors:  Anuj Khandelwal; Jessica A Hall; Brian S J Blagg
Journal:  J Org Chem       Date:  2013-08-01       Impact factor: 4.354

2.  In situ label-free imaging for visualizing the biotransformation of a bioactive polyphenol.

Authors:  Yoon Hee Kim; Yoshinori Fujimura; Takatoki Hagihara; Masako Sasaki; Daichi Yukihira; Tatsuhiko Nagao; Daisuke Miura; Shinichi Yamaguchi; Kazunori Saito; Hiroshi Tanaka; Hiroyuki Wariishi; Koji Yamada; Hirofumi Tachibana
Journal:  Sci Rep       Date:  2013-09-30       Impact factor: 4.379

3.  MALDI Mass Spectrometry Imaging for Visualizing In Situ Metabolism of Endogenous Metabolites and Dietary Phytochemicals.

Authors:  Yoshinori Fujimura; Daisuke Miura
Journal:  Metabolites       Date:  2014-05-09

Review 4.  A Phytochemical-Sensing Strategy Based on Mass Spectrometry Imaging and Metabolic Profiling for Understanding the Functionality of the Medicinal Herb Green Tea.

Authors:  Yoshinori Fujimura; Daisuke Miura; Hirofumi Tachibana
Journal:  Molecules       Date:  2017-09-27       Impact factor: 4.411

5.  Use of positron emission tomography for real-time imaging of biodistribution of green tea catechin.

Authors:  Kosuke Shimizu; Tomohiro Asakawa; Norihiro Harada; Dai Fukumoto; Hideo Tsukada; Tomohiro Asai; Shizuo Yamada; Toshiyuki Kan; Naoto Oku
Journal:  PLoS One       Date:  2014-02-03       Impact factor: 3.240

  5 in total

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