Literature DB >> 21131762

Microspheres in cancer therapy.

M S Rajput1, P Agrawal.   

Abstract

Cancer microsphere technology is the latest trend in cancer therapy. It helps the pharmacist to formulate the product with maximum therapeutic value and minimum or negligible range side effects. Cancer is a disease in which the abnormal cells are quite similar to the normal cells, with just minute genetic or functional change. A major disadvantage of anticancer drugs is their lack of selectivity for tumor tissue alone, which causes severe side effects and results in low cure rates. Thus, it is very difficult to target abnormal cells by the conventional method of the drug delivery system. Microsphere technology is probably the only method that can be used for site-specific action, without causing significant side effects on normal cells. This review article describes various microspheres that have been prepared or formulated to exploit microsphere technology for targeted drug therapy in various cancers. We looked at the usefulness of microspheres as a tool for cancer therapy. The current review has been done using PubMed and Medline search with keywords.

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Year:  2010        PMID: 21131762     DOI: 10.4103/0019-509X.73547

Source DB:  PubMed          Journal:  Indian J Cancer        ISSN: 0019-509X            Impact factor:   1.224


  8 in total

1.  In vivo investigation of ceftiofur-loaded gelatin and PLGA microspheres in beagle dogs.

Authors:  Zhihui Hao; Leilei Wang; Kefeng Xiao; Yongda Zhao; Ming Zou; Qidi Zhang; Zhaopeng Ding; Fenfang Yang; Baohan Qu
Journal:  J Mater Sci Mater Med       Date:  2013-01-26       Impact factor: 3.896

Review 2.  Nanomedicine: a primer for surgeons.

Authors:  K K Y Wong; X L Liu
Journal:  Pediatr Surg Int       Date:  2012-08-15       Impact factor: 1.827

3.  Negatively charged AuNP modified with monoclonal antibody against novel tumor antigen FAT1 for tumor targeting.

Authors:  Li Fan; Susanna Campagnoli; Hong Wu; Alberto Grandi; Matteo Parri; Elisa De Camilli; Guido Grandi; Giuseppe Viale; Piero Pileri; Renata Grifantini; Chaojun Song; Boquan Jin
Journal:  J Exp Clin Cancer Res       Date:  2015-09-15

4.  (210)Po microsphere radiological design for tumor vascular disruption.

Authors:  J J Bevelacqua
Journal:  PeerJ       Date:  2015-08-04       Impact factor: 2.984

5.  Polylactic-co-glycolic acid microspheres containing three neurotrophic factors promote sciatic nerve repair after injury.

Authors:  Qun Zhao; Zhi-Yue Li; Ze-Peng Zhang; Zhou-Yun Mo; Shi-Jie Chen; Si-Yu Xiang; Qing-Shan Zhang; Min Xue
Journal:  Neural Regen Res       Date:  2015-09       Impact factor: 5.135

6.  Tumor vascular disruption using various radiation types.

Authors:  Jj Bevelacqua
Journal:  PeerJ       Date:  2014-04-01       Impact factor: 2.984

Review 7.  Elastin-like polypeptides as a promising family of genetically-engineered protein based polymers.

Authors:  Tomasz Kowalczyk; Katarzyna Hnatuszko-Konka; Aneta Gerszberg; Andrzej K Kononowicz
Journal:  World J Microbiol Biotechnol       Date:  2014-04-04       Impact factor: 3.312

Review 8.  Anticancer Properties of Essential Oils and Other Natural Products.

Authors:  K Blowman; M Magalhães; M F L Lemos; C Cabral; I M Pires
Journal:  Evid Based Complement Alternat Med       Date:  2018-03-25       Impact factor: 2.629

  8 in total

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