BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (AE-COPD) necessitating hospital admission have a major impact on patient outcome and management costs. We examined temporal trends in AE-COPD-related hospital admissions in France between 1998 and 2007. METHODS: Data were obtained from the French national hospital discharge database for patients aged at least 25 years. AE-COPD was identified with both a "narrow" and a "broad" definition, according to the position (primary or associated) of diagnoses, in order to ensure robustness. RESULTS: In 2007, among adults aged 25 years or more, the crude AE-COPD-related admission rates were 23/10000 in men and 10/10000 in women using the narrow definition. Using the broad definition, these rates were respectively 38 and 16/10000. With the narrow definition, the annual number of AE-COPD-related admissions increased by 38% between 1998 and 2007, while in-hospital lethality decreased from 7.6% to 6.0%. The proportion of male patients decreased from 72% to 68%. Similar trends were found using the broad definition. The age-standardized AE-COPD-related admission rate increased by 4.4% per year in women and by 1.6% per year in men with the narrow definition, and by respectively 3.8% and 1.2% with the broad definition. A strong seasonal pattern of admissions for AE-COPD was found, matching that of general practitioners visits for influenza-like illness. CONCLUSION: Hospitalization rates for AE-COPD have increased in France in recent years, especially among women. By contrast, AE-COPD-related in-hospital lethality has decreased.
BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (AE-COPD) necessitating hospital admission have a major impact on patient outcome and management costs. We examined temporal trends in AE-COPD-related hospital admissions in France between 1998 and 2007. METHODS: Data were obtained from the French national hospital discharge database for patients aged at least 25 years. AE-COPD was identified with both a "narrow" and a "broad" definition, according to the position (primary or associated) of diagnoses, in order to ensure robustness. RESULTS: In 2007, among adults aged 25 years or more, the crude AE-COPD-related admission rates were 23/10000 in men and 10/10000 in women using the narrow definition. Using the broad definition, these rates were respectively 38 and 16/10000. With the narrow definition, the annual number of AE-COPD-related admissions increased by 38% between 1998 and 2007, while in-hospital lethality decreased from 7.6% to 6.0%. The proportion of male patients decreased from 72% to 68%. Similar trends were found using the broad definition. The age-standardized AE-COPD-related admission rate increased by 4.4% per year in women and by 1.6% per year in men with the narrow definition, and by respectively 3.8% and 1.2% with the broad definition. A strong seasonal pattern of admissions for AE-COPD was found, matching that of general practitioners visits for influenza-like illness. CONCLUSION: Hospitalization rates for AE-COPD have increased in France in recent years, especially among women. By contrast, AE-COPD-related in-hospital lethality has decreased.
Authors: Thomas G Poder; Christian R C Kouakou; Pierre-Alexandre Bouchard; Véronique Tremblay; Sébastien Blais; François Maltais; François Lellouche Journal: BMJ Open Date: 2018-01-23 Impact factor: 2.692
Authors: Jonas Poucineau; Tristan Delory; Nathanaël Lapidus; Gilles Hejblum; Christos Chouaïd; Sophie Le Cœur; Myriam Khlat Journal: Front Med (Lausanne) Date: 2022-09-16
Authors: Julián Librero; Berta Ibañez-Beroiz; Salvador Peiró; M Ridao-López; Clara L Rodríguez-Bernal; Francisco J Gómez-Romero; Enrique Bernal-Delgado Journal: BMC Health Serv Res Date: 2016-08-09 Impact factor: 2.655
Authors: Roger A Morbey; Andre Charlett; Iain Lake; James Mapstone; Richard Pebody; James Sedgwick; Gillian E Smith; Alex J Elliot Journal: PLoS One Date: 2020-02-10 Impact factor: 3.240