PURPOSE: We analyzed changes in aesthetic and functional outcome over time after breast conserving therapy. Our special interest resides in the question of whether these aspects gain or loose their influence on quality of life (QoL) with temporal progress. PATIENTS AND METHODS: This prospective single centre cohort study included 138 patients, treated with breast conserving surgery and consecutive radiotherapy. Patients completed two questionnaires one week and one year after surgery: the BCTOS (Breast Cancer Treatment Outcome Scale) to measure Functional, Aesthetic, and Breast Sensitivity Status and the EORTC (European Organisation for Research and Treatment of Cancer) C30-BR23 to assess QoL. We applied correlation and multiple regression analysis as statistical methods. RESULTS: Aesthetic and Functional Status did not change significantly over one year, whereas Breast Sensitivity Status and several QoL subscales showed significant improvement (p < 0.0001). Correlations between BCTOS scales and EORTC subscales remain similar over time. Functional and Aesthetic Status kept a strong impact on global health (Spearman's Rho = -0.28 to -0.45 depending on time of assessment). Increasing age and poorer Functional Status shortly after surgery are predictors of a decline in global health over one year (p < 0.001). CONCLUSION: Functional and aesthetic outcome after breast conserving surgery maintain their impact on QoL over a one year follow-up period and are valuable predictors of QoL.
PURPOSE: We analyzed changes in aesthetic and functional outcome over time after breast conserving therapy. Our special interest resides in the question of whether these aspects gain or loose their influence on quality of life (QoL) with temporal progress. PATIENTS AND METHODS: This prospective single centre cohort study included 138 patients, treated with breast conserving surgery and consecutive radiotherapy. Patients completed two questionnaires one week and one year after surgery: the BCTOS (Breast Cancer Treatment Outcome Scale) to measure Functional, Aesthetic, and Breast Sensitivity Status and the EORTC (European Organisation for Research and Treatment of Cancer) C30-BR23 to assess QoL. We applied correlation and multiple regression analysis as statistical methods. RESULTS: Aesthetic and Functional Status did not change significantly over one year, whereas Breast Sensitivity Status and several QoL subscales showed significant improvement (p < 0.0001). Correlations between BCTOS scales and EORTC subscales remain similar over time. Functional and Aesthetic Status kept a strong impact on global health (Spearman's Rho = -0.28 to -0.45 depending on time of assessment). Increasing age and poorer Functional Status shortly after surgery are predictors of a decline in global health over one year (p < 0.001). CONCLUSION: Functional and aesthetic outcome after breast conserving surgery maintain their impact on QoL over a one year follow-up period and are valuable predictors of QoL.
Authors: Elles M F van de Voort; Taco M A L Klem; Gerson M Struik; Erwin Birnie; Renata H J A Sinke; Ali Ghandi Journal: Br J Radiol Date: 2020-07-20 Impact factor: 3.039
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Authors: A T P M Brands-Appeldoorn; A J G Maaskant-Braat; L Janssen; L A D M van Osch; V C G Tjan-Heijnen; R M H Roumen Journal: Breast Cancer Date: 2021-08-26 Impact factor: 4.239
Authors: Florian Fitzal; Michael Bolliger; Daniela Dunkler; Angelika Geroldinger; Luca Gambone; Jörg Heil; Fabian Riedel; Jana de Boniface; Camilla Andre; Zoltan Matrai; Dávid Pukancsik; Regis R Paulinelli; Valerijus Ostapenko; Arvydas Burneckis; Andrej Ostapenko; Edvin Ostapenko; Francesco Meani; Yves Harder; Marta Bonollo; Andrea S M Alberti; Christoph Tausch; Bärbel Papassotiropoulos; Ruth Helfgott; Dietmar Heck; Hans-Jörg Fehrer; Markus Acko; Peter Schrenk; Elisabeth K Trapp; Pristauz-Telsnigg Gunda; Paliczek Clara; Giacomo Montagna; Mathilde Ritter; Jens-Uwe Blohmer; Sander Steffen; Laszlo Romics; Elizabeth Morrow; Katharina Lorenz; Mathias Fehr; Walter Paul Weber Journal: Ann Surg Oncol Date: 2021-10-13 Impact factor: 5.344