Literature DB >> 21130369

Reproducibility of reported in utero exposure to tobacco smoke.

Lea A Cupul-Uicab1, Xibiao Ye, Rolv Skjaerven, Kjell Haug, Matthew P Longnecker.   

Abstract

PURPOSE: In studies of the fetal origins of disease and life course epidemiology, measures of fetal exposure may be based on information reported by the adults who were exposed in utero. In particular, the full spectrum of consequences of in utero exposure to maternal tobacco smoking is now an area of active investigation, and the ability to report such exposure reproducibly is of interest. We evaluated the reproducibility of in utero exposure to tobacco smoke, reported by the adult daughter during consecutive pregnancies.
METHODS: This study was based on 11,257 women who enrolled for more than one pregnancy in the Norwegian Mother and Child Cohort Study (MoBa). Participants completed a questionnaire around 17 weeks of gestation, which asked about their in utero exposure to tobacco smoke. Kappa statistics were calculated. Determinants of agreement were evaluated using logistic regression.
RESULTS: Weighted Kappa for in utero exposure for the first and second reports was 0.80. Determinants of agreement were higher education (better) and longer time between reports (worse).
CONCLUSIONS: Information on in utero exposure to maternal tobacco smoking provided by adult women was highly reproducible in this population. Published by Elsevier Inc.

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Year:  2011        PMID: 21130369      PMCID: PMC3005127          DOI: 10.1016/j.annepidem.2010.10.008

Source DB:  PubMed          Journal:  Ann Epidemiol        ISSN: 1047-2797            Impact factor:   3.797


  22 in total

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2.  In utero exposure to maternal smoking and women's risk of fetal loss in the Norwegian Mother and Child Cohort (MoBa).

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