Literature DB >> 21128724

Applications of aptamers in nanodelivery systems in cancer, eye and inflammatory diseases.

Jagat R Kanwar1, Rajiv R Mohan, Rupinder K Kanwar, Kislay Roy, Raj Bawa.   

Abstract

Aptamers are an interesting class of molecules that have potential in many facets of human health. They are characterized by high affinity and specificity to their targets, are small in size, have similar properties to antibodies, but are made synthetically. All of these properties, among others, give aptamers the potential to diagnose, image and treat like no other molecules. By combining the unique properties of aptamers with the ever expanding field of nanotechnology and all it has to offer, we are entering a very promising new area of targeted nanodelivery treatments. These treatments have found success in the complex disease processes of cancer, eye and inflammatory diseases.

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Year:  2010        PMID: 21128724     DOI: 10.2217/nnm.10.115

Source DB:  PubMed          Journal:  Nanomedicine (Lond)        ISSN: 1743-5889            Impact factor:   5.307


  7 in total

Review 1.  Gene therapy in the cornea: 2005--present.

Authors:  Rajiv R Mohan; Jonathan C K Tovey; Ajay Sharma; Ashish Tandon
Journal:  Prog Retin Eye Res       Date:  2011-09-28       Impact factor: 21.198

Review 2.  Clinical applications of nucleic acid aptamers in cancer.

Authors:  Xiaoyu Pei; Jun Zhang; Jie Liu
Journal:  Mol Clin Oncol       Date:  2014-02-10

Review 3.  Quantitative detection of neurotransmitter using aptamer: From diagnosis to therapeutics.

Authors:  Koel Sinha; Chitrangada DAS Mukhopadhyay
Journal:  J Biosci       Date:  2020       Impact factor: 1.826

Review 4.  Aptamer and its applications in neurodegenerative diseases.

Authors:  Jing Qu; Shuqing Yu; Yuan Zheng; Yan Zheng; Hui Yang; Jianliang Zhang
Journal:  Cell Mol Life Sci       Date:  2016-08-25       Impact factor: 9.261

Review 5.  Chimeric aptamers in cancer cell-targeted drug delivery.

Authors:  Jagat R Kanwar; Kislay Roy; Rupinder K Kanwar
Journal:  Crit Rev Biochem Mol Biol       Date:  2011-09-28       Impact factor: 8.250

6.  DNA aptamer evolved by cell-SELEX for recognition of prostate cancer.

Authors:  Yuanyuan Wang; Yun Luo; Tao Bing; Zheng Chen; Minhua Lu; Nan Zhang; Dihua Shangguan; Xin Gao
Journal:  PLoS One       Date:  2014-06-23       Impact factor: 3.240

7.  Target-specific delivery of doxorubicin to retinoblastoma using epithelial cell adhesion molecule aptamer.

Authors:  Nithya Subramanian; Vaishnavi Raghunathan; Jagat R Kanwar; Rupinder K Kanwar; Sailaja V Elchuri; Vikas Khetan; Subramanian Krishnakumar
Journal:  Mol Vis       Date:  2012-11-22       Impact factor: 2.367

  7 in total

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