Nonnegative least-squares truncated singular value decomposition to particle size distribution inversion from dynamic light scattering data.

The weak symmetry relationship between the relative error and solution norm holds in our developed nonnegative least-squares truncated singular value decomposition method. By using this relationship to specify the optimal regularization parameters, we applied the proposed algorithm to recover particle size distribution from dynamic light scattering (DLS) data. Simulated results and experimental validity demonstrate that the proposed method, which compliments the CONTIN algorithm, might serve as a powerful and simple approach to the inverse problem in DLS.