OBJECTIVE: To determine whether individuals with simple silicosis have obstructive and restrictive decrements. METHODS: The prevalence of spirometric abnormalities by radiograph profusion, smoking, duration, and latency from first silica exposure was evaluated among confirmed silicotics. RESULTS: Among 526 silicotics, 17.3% who had never smoked and 26.5% of smokers had obstruction, 30.1% and 28.1% had restriction, and 22.4% and 25.7% had a mixed obstructive and restrictive pattern. Individuals with category 3 profusion or progressive massive fibrosis were more likely to have abnormalities. CONCLUSION: Both obstructive and restrictive patterns were observed regardless of smoking status with a low profusion category of simple silicosis. There was an increased prevalence of restrictive changes with increased profusion. After controlling for age, smoking, and duration of exposure to silica, there was a statistically significant increased risk of obstructive and mixed changes with progressive massive fibrosis.
OBJECTIVE: To determine whether individuals with simple silicosis have obstructive and restrictive decrements. METHODS: The prevalence of spirometric abnormalities by radiograph profusion, smoking, duration, and latency from first silica exposure was evaluated among confirmed silicotics. RESULTS: Among 526 silicotics, 17.3% who had never smoked and 26.5% of smokers had obstruction, 30.1% and 28.1% had restriction, and 22.4% and 25.7% had a mixed obstructive and restrictive pattern. Individuals with category 3 profusion or progressive massive fibrosis were more likely to have abnormalities. CONCLUSION: Both obstructive and restrictive patterns were observed regardless of smoking status with a low profusion category of simple silicosis. There was an increased prevalence of restrictive changes with increased profusion. After controlling for age, smoking, and duration of exposure to silica, there was a statistically significant increased risk of obstructive and mixed changes with progressive massive fibrosis.
Authors: Veruscka Leso; Luca Fontana; Rosaria Romano; Paola Gervetti; Ivo Iavicoli Journal: Int J Environ Res Public Health Date: 2019-02-16 Impact factor: 3.390