Literature DB >> 2112423

Transforming growth factor-beta and ovarian carcinoma cells: regulation of proliferation and surface antigen expression.

C Marth1, T Lang, A Koza, I Mayer, G Daxenbichler.   

Abstract

Transforming growth factor-beta (TGF-beta) is a multifunctional peptide regulating several processes in ovarian cells. The growth of ovarian carcinoma cell lines (OVCAR-3, HTB-77, 2780 and CRL-1572) was reduced by TGF-beta in a dose related manner. The antiproliferative activity was not improved by combination with other biological response modifiers. Treatment with TGF-beta augmented the expression of interferon-gamma induced class I and II antigens of the major histocompatibility complex. The presentation of another antigen namely the tumor marker CA-125 on the cell surface was markedly reduced by TGF-beta.

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Year:  1990        PMID： 2112423     DOI： 10.1016/0304-3835(90)90106-8

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  6 in total

1.  Dynamics of protein 27 of avian leukosis virus and transforming growth factor beta2 in lymphoid leukosis susceptible and resistant broiler chicken breeding stock.

Authors:  E K Barbour; M Bouljihad; B Hamdar; W Sakr; A Eid; B Safieh-Garabedian
Journal:  Vet Res Commun       Date:  1999-05       Impact factor: 2.459

2.  Transforming growth factor-beta synthesis by human peritoneal mesothelial cells. Induction by interleukin-1.

Authors:  F A Offner; H Feichtinger; S Stadlmann; P Obrist; C Marth; P Klingler; B Grage; M Schmahl; C Knabbe
Journal:  Am J Pathol       Date:  1996-05       Impact factor: 4.307

3.  Differential expression of cytokine transcripts in human epithelial ovarian carcinoma by solid tumour specimens, peritoneal exudate cells containing tumour, tumour-infiltrating lymphocyte (TIL)-derived T cell lines and established tumour cell lines.

Authors:  M A Nash; R Lenzi; C L Edwards; J J Kavanagh; A P Kudelka; C F Verschraegen; C D Platsoucas; R S Freedman
Journal:  Clin Exp Immunol       Date:  1998-05       Impact factor: 4.330

4.  Transforming growth factor-beta mRNA expression and growth control of human ovarian carcinoma cells.

Authors:  J M Bartlett; G J Rabiasz; W N Scott; S P Langdon; J F Smyth; W R Miller
Journal:  Br J Cancer       Date:  1992-05       Impact factor: 7.640

5.  TGF-β isoforms induce EMT independent migration of ovarian cancer cells.

Authors:  Jingfang Gao; Yihong Zhu; Mikael Nilsson; Karin Sundfeldt
Journal:  Cancer Cell Int       Date:  2014-09-09       Impact factor: 5.722

6.  In vivo anti-V-ATPase antibody treatment delays ovarian tumor growth by increasing antitumor immune responses.

Authors:  Arpita Kulshrestha; Gajendra K Katara; Safaa A Ibrahim; Valerie E Riehl; Sylvia Schneiderman; Mahmood Bilal; Alexandria N Young; Shayna Levine; Sara Fleetwood; James Dolan; Alice Gilman-Sachs; Kenneth D Beaman
Journal:  Mol Oncol       Date:  2020-09-10       Impact factor: 6.603
  6 in total

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