Literature DB >> 2112384

Purification and properties of phospholipase A2 from the venom of scorpion, (Heterometrus fulvipes).

M Ramanaiah1, P R Parthasarathy, B Venkaiah.   

Abstract

Phospholipase A2 was purified about 78 fold from the venom of scorpion Heterometrus fulvipes. The molecular weight of the enzyme was found to be 16,000 and it was optimally active at pH 7.4 and at 50 degrees C. The Km value of the enzyme was 1.8 x 10(-3) M. Calcium, Magnesium and Zinc ions stimulated whereas Mercury ion and EDTA inhibited the enzyme activity. This enzyme exhibited fluorescence emission maximum between 310-320 nm.

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Year:  1990        PMID： 2112384

Source DB:  PubMed          Journal:  Biochem Int        ISSN： 0158-5231


  5 in total

1.  Zinc (Zn2+) binds to and stimulates the activity of group I but not group II phospholipase A2.

Authors:  M Lindahl; C Tagesson
Journal:  Inflammation       Date:  1996-12       Impact factor: 4.092

Review 2.  Therapeutic Potential of Bee and Scorpion Venom Phospholipase A2 (PLA2): A Narrative Review.

Authors:  Parisa Soltan-Alinejad; Hamzeh Alipour; Davood Meharabani; Kourosh Azizi
Journal:  Iran J Med Sci       Date:  2022-07

3.  Molecular Characterization and In Silico Analyses of Maurolipin Structure as a Secretory Phospholipase A 2 (sPLA2) from Venom Glands of Iranian Scorpio maurus (Arachnida: Scorpionida).

Authors:  Parisa Soltan-Alinejad; Hamzeh Alipour; Aboozar Soltani; Qasem Asgari; Amin Ramezani; Davood Mehrabani; Kourosh Azizi
Journal:  J Trop Med       Date:  2022-10-03

4.  Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones).

Authors:  Elisabeth F Schwartz; Elia Diego-Garcia; Ricardo C Rodríguez de la Vega; Lourival D Possani
Journal:  BMC Genomics       Date:  2007-05-16       Impact factor: 3.969

5.  Pioneering Study on Rhopalurus crassicauda Scorpion Venom: Isolation and Characterization of the Major Toxin and Hyaluronidase.

Authors:  Caio B Abreu; Karla C F Bordon; Felipe A Cerni; Isadora S Oliveira; Carla Balenzuela; Gabriel M Alexandre-Silva; Karina F Zoccal; Mouzarllem B Reis; Gisele A Wiezel; Steve Peigneur; Ernesto L Pinheiro-Júnior; Jan Tytgat; Tiago M Cunha; Loic Quinton; Lúcia H Faccioli; Eliane C Arantes; Umberto Zottich; Manuela B Pucca
Journal:  Front Immunol       Date:  2020-08-20       Impact factor: 7.561
  5 in total

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