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Literature DB >> 211236

The role of cyclic AMP in parathyroid hormone action in the toad bladder.

Abstract

Parathyroid hormone (PTH) inhibited active transport of inorganic phosphate and stimulated an increase in cyclic AMP concentration in the urinary bladder of the toad, Bufo marinus. Active transport of phosphate in the toad bladder was also inhibited by an analog of cyclic AMP (dibutyryl cyclic AMP) and by other drugs (pitressin and theophylline) which increase toad bladder intracellular cyclic AMP concentration. These data support the concept that cyclic AMP may be the mediator of PTH-induced phosphate transport inhibition in the toad bladder.

Entities: Chemical Species

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Year: 1978 PMID： 211236 DOI： 10.1007/bf01871997

Source DB: PubMed Journal: J Membr Biol ISSN： 0022-2631 Impact factor: 1.843

17 in total

1. CALCIUM INHIBITION OF THE ACTION OF VASOPRESSIN ON THE URINARY BLADDER OF THE TOAD.

Authors: M J PETERSEN; I S EDELMAN
Journal: J Clin Invest Date: 1964-04 Impact factor: 14.808

2. Stimulation of osmotic water flow in toad bladder by prostaglandin E1. Evidence for different compartments of cyclic AMP.

Authors: J Flores; P A Witkum; B Beckman; G W Sharp
Journal: J Clin Invest Date: 1975-08 Impact factor: 14.808

3. Response of phosphate transport to parathyroid hormone in segments of rabbit nephron.

Authors: V W Dennis; E Bello-Reuss; R R Robinson
Journal: Am J Physiol Date: 1977-07

4. Effect of prostaglandin E1 on sodium transport and osmotic water flow in the toad bladder.

Authors: L C Lipson; G W Sharp
Journal: Am J Physiol Date: 1971-04

5. Mechanism of the blunted phosphaturia in saline-loaded thyroparathyroidectomized dogs.

Authors: L H Beck; M Goldberg
Journal: Kidney Int Date: 1974-07 Impact factor: 10.612

6. Urinary excretion of inorganic phosphates and free fatty acids levels in the rat sera after a single injection of lysine-vasopressin.

Authors: J Kolousek
Journal: Arch Int Physiol Biochim Date: 1968-04

The role of cyclic AMP in parathyroid hormone action in the toad bladder.

1. CALCIUM INHIBITION OF THE ACTION OF VASOPRESSIN ON THE URINARY BLADDER OF THE TOAD.

2. Stimulation of osmotic water flow in toad bladder by prostaglandin E1. Evidence for different compartments of cyclic AMP.

3. Response of phosphate transport to parathyroid hormone in segments of rabbit nephron.

4. Effect of prostaglandin E1 on sodium transport and osmotic water flow in the toad bladder.

5. Mechanism of the blunted phosphaturia in saline-loaded thyroparathyroidectomized dogs.

6. Urinary excretion of inorganic phosphates and free fatty acids levels in the rat sera after a single injection of lysine-vasopressin.

7. Effect of vasopressin on the renal excretion of phosphate in man.

8. Active phosphate transport across the urinary bladder of the toad, Bufo marinus.

9. The effect of vasopressin on phosphate transport in the proximal tubule of the dog.

10. Tracer microinjection study of renal tubular phosphate reabsorption in the rat.

1. Cyclic AMP as a second messenger in the skeletal actions of parathyroid hormone: a decade-old hypothesis.