Literature DB >> 21123067

Glycosylated nordihydroguaiaretic acids as anti-cancer agents.

Jih Ru Hwu1, Chuan-I Hsu, Ming-Hua Hsu, Yu-Chuan Liang, Ru Chih C Huang, Yuan C Lee.   

Abstract

Three perglycosylated nordihydroguaiaretic acids (NDGA) were synthesized through the Huiseng 1,3-dipolar cycloaddition reaction. These sugar-NDGA conjugates containing triazole-linkages possessed good solubility in water. NDGA-(triazol-galactose)(4) (12b) and NDGA-(triazol-glucose)(4) (12c) were found to act as inhibitors against human hepatocellular carcinoma Hep3B cells in culture.
Copyright © 2010. Published by Elsevier Ltd.

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Year:  2010        PMID： 21123067     DOI： 10.1016/j.bmcl.2010.10.137

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

1.  Glucose conjugation for the specific targeting and treatment of cancer.

Authors:  Emilia C Calvaresi; Paul J Hergenrother
Journal:  Chem Sci       Date:  2013-06       Impact factor: 9.825

2.  Phase I study of terameprocol in patients with recurrent high-grade glioma.

Authors:  Stuart A Grossman; Xiaobu Ye; David Peereboom; Myrna R Rosenfeld; Tom Mikkelsen; Jeffrey G Supko; Serena Desideri
Journal:  Neuro Oncol       Date:  2012-02-08       Impact factor: 12.300

3.  Synthesis and Cytotoxic Property of Annonaceous Acetogenin Glycoconjugates.

Authors:  Jing-Fang Shi; Ping Wu; Xiao-Li Cheng; Xiao-Yi Wei; Zi-Hua Jiang
Journal:  Drug Des Devel Ther       Date:  2020-11-17       Impact factor: 4.162

Review 4.  Reactive oxygen species and antioxidant defense in human gastrointestinal diseases.

Authors:  Peter Patlevič; Janka Vašková; Pavol Švorc; Ladislav Vaško; Pavol Švorc
Journal:  Integr Med Res       Date:  2016-07-29
  4 in total

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