Literature DB >> 21122997

Treatment of post-burn leucoderma with non-cultured melanocyte-keratinocyte transplantation (MKTP).

Sanjeev V Mulekar1, Ahmed Al Issa, Abdullah Al Eisa.   

Abstract

INTRODUCTION: Deep burns often result in hypo-pigmentation, referred to as leucoderma which has a similar psychosocial impact on the patients as that of vitiligo. Several tissue grafting methods have been reported to treat post-burn leucoderma.
METHODS: A simple method consisting of harvesting a donor skin sample, preparation of an epidermal cell suspension and the transplantation of the cell suspension on to a dermabraded recipient area, was performed in a clean procedure room. No special laboratory set-up was used for the cell separation procedure. Patients were treated with 18 sessions of excimer laser starting 1 month post-operatively, to hasten the repigmentation. OBSERVATION: Of the 10 patients treated with MKTP, 3 were lost to follow-up. The remaining 7 patients showed repigmentation ranging from 90% to 100% with good color matching.
CONCLUSION: MKTP is an effective method to treat post-burn leucoderma. No special precautions are required to treat any anatomical site or uneven scarred surface.
Copyright © 2010 Elsevier Ltd and ISBI. All rights reserved.

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Year:  2010        PMID: 21122997     DOI: 10.1016/j.burns.2010.08.014

Source DB:  PubMed          Journal:  Burns        ISSN: 0305-4179            Impact factor:   2.744


  4 in total

1.  Combination of medical needling and non-cultured autologous skin cell transplantation (renovacell) for repigmentation of hypopigmented burn scars in children and young people.

Authors:  K H Busch; R Bender; N Walezko; H Aziz; M A Altintas; M C Aust
Journal:  Ann Burns Fire Disasters       Date:  2016-06-30

2.  Dyspigmented hypertrophic scars: Beyond skin color.

Authors:  Abdulnaser Alkhalil; Bonnie C Carney; Taryn E Travis; Seid Muhie; Stacy Ann Miller; Jessica C Ramella-Roman; Pehman Ghassemi; Rasha Hammamieh; Marti Jett; Lauren T Moffatt; Jeffrey W Shupp
Journal:  Pigment Cell Melanoma Res       Date:  2019-04-05       Impact factor: 4.693

3.  Treatment Strategies for Hypopigmentation in the Context of Burn Hypertrophic Scars.

Authors:  Bonnie C Carney; Jacqueline P McKesey; Dean S Rosenthal; Jeffrey W Shupp
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-01-18

4.  Comparison of intradermal injection of autologous epidermal cell suspension vs. spraying of these cells on dermabraded surface of skin of patients with post-burn hypopigmentation.

Authors:  Ahrari Iman; Mohamadi Ali Akbar; Khosravi Maharlooei Mohsen; Farsi Ali; Attar Armin; Ahrari Sajjad; Monabati Ahmad; Mahsa Ghavipisheh; Rahnama Leila
Journal:  Indian J Dermatol       Date:  2013-05       Impact factor: 1.494

  4 in total

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