Literature DB >> 21121766

Neonatal and infant mandibular distraction as an alternative to tracheostomy in severe obstructive sleep apnea.

Jeffrey Hammoudeh1, Vijay K Bindingnavele, Brian Davis, Sally L Davidson Ward, Pedro A Sanchez-Lara, Grant Kleiber, Sheila S Nazarian Mobin, Cameron S Francis, Mark M Urata.   

Abstract

CONTEXT: Surgical management for severe obstructive sleep apnea has been tracheostomy, which has significant morbidity.
OBJECTIVE: To determine the efficacy of internal mandibular distraction in treating severe obstructive sleep apnea in infants and neonates.
DESIGN: Retrospective review of medical records of 29 patients who underwent internal mandibular distraction for obstructive sleep apnea secondary to micrognathia.
SETTING: Nonprofit, academic, pediatric medical center. PATIENTS: A total of 29 infants with obstructive sleep apnea were studied. Nine were included in the respiratory failure group requiring intubation prior to distraction surgery. The other 20 were included in the respiratory distress group and underwent preoperative polysomnography that assessed the severity of obstructive sleep apnea as measured by the apnea-hypopnea index. One patient expired following surgery; the remaining 28 underwent postoperative polysomnography determining their postoperative apnea-hypopnea index.
INTERVENTIONS: Bilateral mandibular distraction with internal microdistractors. MAIN OUTCOME MEASURE: Improvement in the apnea-hypopnea index or extubation.
RESULTS: The nine respiratory failure patients avoided tracheostomy and were successfully extubated postdistraction. Eight in this group had postoperative polysomnographies showing a mean apnea-hypopnea index of 3.13 (range, 0 to 13.9). All 20 patients in the respiratory distress group underwent polysomnography and showed improved apnea-hypopnea indices (p < .001). The mean pre-op apnea-hypopnea index was 39.7 (range, 4.5 to 177), and the mean post-op apnea-hypopnea index was 5.8 (range, 0 to 34). Average improvement in the apnea-hypopnea index was 33.9. The mean follow-up period was 18.7 months (1.6 to 45.2 months).
CONCLUSIONS: Infants with micrognathia and obstructive sleep apnea may avoid tracheostomy and its inherent risks and complications by undergoing internal mandibular distraction, which is a viable alternative to tracheostomy.

Entities:  

Mesh:

Year:  2010        PMID: 21121766     DOI: 10.1597/10-069

Source DB:  PubMed          Journal:  Cleft Palate Craniofac J        ISSN: 1055-6656


  8 in total

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Review 2.  Sleep and respiratory outcomes in neonates with Pierre Robin sequence: a concise review.

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Journal:  Sleep Breath       Date:  2019-06-25       Impact factor: 2.816

Review 3.  Surgical Management and Outcomes of Pierre Robin Sequence: A Comparison of Mandibular Distraction Osteogenesis and Tongue-Lip Adhesion.

Authors:  Rosaline S Zhang; Ian C Hoppe; Jesse A Taylor; Scott P Bartlett
Journal:  Plast Reconstr Surg       Date:  2018-08       Impact factor: 4.730

Review 4.  A systematic review on the outcome of mandibular distraction osteogenesis in infants suffering Robin sequence.

Authors:  Emma C Paes; Aebele B Mink van der Molen; Marvick S M Muradin; Lucienne Speleman; Frea Sloot; Moshe Kon; Corstiaan C Breugem
Journal:  Clin Oral Investig       Date:  2013-05-31       Impact factor: 3.573

5.  Polysomnography-guided mandibular distraction osteogenesis in Pierre Robin sequence patients.

Authors:  Rashi Kochhar; Vikash Modi; Neranjan de Silva; Seyni Gueye-Ndiaye; Jay M Neugarten; Mary J Ward; Linda M Gerber; Anjile An; Elizabeth Mauer; Haviva Veler
Journal:  J Clin Sleep Med       Date:  2022-07-01       Impact factor: 4.324

Review 6.  Distraction osteogenesis as a treatment of obstructive sleep apnea syndrome: A systematic review.

Authors:  Wai Kin Tsui; Yanqi Yang; Lim Kwong Cheung; Yiu Yan Leung
Journal:  Medicine (Baltimore)       Date:  2016-09       Impact factor: 1.889

7.  Polysomnographic findings in infants with Pierre Robin sequence.

Authors:  Abdullah Khayat; Saadoun Bin-Hassan; Suhail Al-Saleh
Journal:  Ann Thorac Med       Date:  2017 Jan-Mar       Impact factor: 2.219

8.  Normal Neonatal Sleep Defined: Refining Patient Selection and Interpreting Sleep Outcomes for Mandibular Distraction.

Authors:  Melissa D Kanack; Neal Nakra; Irfan Ahmad; Raj M Vyas
Journal:  Plast Reconstr Surg Glob Open       Date:  2022-01-19
  8 in total

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