Literature DB >> 21119584

A fatal case of paraquat ingestion: clinical course and review of pathophysiology.

Douglas P Olson1, Juan A Diaz, Jose Dalio Gomez Jereda.   

Abstract

BACKGROUND: Exposure to the dipyridyl herbicide paraquat can cause many manifestations of toxicity, and is a common method of suicide in developing countries. CASE REPORT: We present a case of a 20 year old healthy gentleman who intentionally overdosed on paraquat in a suicide attempt. He presented to the hospital within 4 hours of ingestion. Despite standard supportive measures, the patient's clinical condition worsened. He developed ulceration of his oral mucosa. He also developed acute non-oliguric renal failure and acute liver injury. After his mental status began to deteriorate, the patient expired.
CONCLUSIONS: There are several therapies that may have helped this patient's condition. An explanation about the pathophysiology of toxicity and updated information on treatment is provided for this common condition with poor prognosis.

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Year:  2010        PMID: 21119584

Source DB:  PubMed          Journal:  Med Sci Monit        ISSN: 1234-1010


  3 in total

Review 1.  Delayed death following paraquat poisoning: three case reports and a literature review.

Authors:  Shahin Shadnia; Alireza Ebadollahi-Natanzi; Saeid Ahmadzadeh; Somayyeh Karami-Mohajeri; Yaghoub Pourshojaei; Hamid Reza Rahimi
Journal:  Toxicol Res (Camb)       Date:  2018-06-12       Impact factor: 3.524

2.  Protective Effects of a Rho Kinase Inhibitor on Paraquat-Induced Acute Lung Injuries in Rats.

Authors:  Lichun Zhang; Qiuhe Li; Zhenning Liu; Wei Liu; Min Zhao
Journal:  Inflammation       Date:  2018-12       Impact factor: 4.092

3.  Hyperamylasemia as an Early Predictor of Mortality in Patients with Acute Paraquat Poisoning.

Authors:  Shuai Liu; Qiang Wang; Rong Zhou; Changbin Li; Dayong Hu; Wen Xue; Tianfu Wu; Chandra Mohan; Ai Peng
Journal:  Med Sci Monit       Date:  2016-04-21
  3 in total

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