Literature DB >> 21116753

Can VEPTR(®) control progression of early-onset kyphoscoliosis? A cohort study of VEPTR(®) patients with severe kyphoscoliosis.

Kent Reinker1, James W Simmons, Vishwas Patil, Zachary Stinson.   

Abstract

BACKGROUND: Kyphoscoliosis is considered a relative contraindication to treatment with the Vertical Expandable Prosthetic Titanium Rib (VEPTR(®); Synthes Inc, Paoli, PA). Nevertheless, patients do present with early-onset kyphoscoliosis and thoracic insufficiency syndrome, and no suitable alternative treatments are currently available. However, it is unclear whether VEPTR(®) is reasonable for treating patients with kyphoscoliosis. QUESTIONS/PURPOSES: We determined whether VEPTR(®) controls progression in patients with kyphoscoliosis and, if so, what methods might be used to improve control of deformity progression in these patients. PATIENTS AND METHODS: We retrospectively reviewed 14 patients who had VEPTR(®) treatment of early-onset kyphoscoliosis. Degrees of kyphosis and scoliosis before, during, and after treatment were measured, and levels of instrumentation, thoracic dimensions, and complications were recorded. Minimum followup was 1.7 years (average, 5.8 years; range, 1.7-12.8 years).
RESULTS: While scoliosis was stabilized, kyphosis increased a mean of 22° at last followup. Supple kyphosis became rigid during treatment. Proximal cradle cutout was a recurring problem. Distal anchors placed too proximally had inadequate lever arms to control kyphosis.
CONCLUSIONS: Progression of kyphosis can be minimized during VEPTR(®) treatment by early extension of the construct to the second ribs bilaterally, distal extension of hybrid constructs to the pelvis, use of bilateral hybrid VEPTR(®) implants, and use of redesigned VEPTR(®) constructs that enhance fixation at the upper end. While our early results suggest these devices control progression of kyphosis, longer followup with more patients will be required to confirm the concept in these patients.

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Year:  2011        PMID: 21116753      PMCID: PMC3069267          DOI: 10.1007/s11999-010-1697-6

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  25 in total

1.  Sagittal plane analysis of adolescent idiopathic scoliosis: the effect of anterior versus posterior instrumentation.

Authors:  John M Rhee; Keith H Bridwell; Douglas S Won; Lawrence G Lenke; Chatupon Chotigavanichaya; Darrell S Hanson
Journal:  Spine (Phila Pa 1976)       Date:  2002-11-01       Impact factor: 3.468

2.  Proximal kyphosis after posterior spinal fusion in patients with idiopathic scoliosis.

Authors:  G A Lee; R R Betz; D H Clements; G K Huss
Journal:  Spine (Phila Pa 1976)       Date:  1999-04-15       Impact factor: 3.468

3.  The characteristics of thoracic insufficiency syndrome associated with fused ribs and congenital scoliosis.

Authors:  Robert M Campbell; Melvin D Smith; Thomas C Mayes; John A Mangos; Donna B Willey-Courand; Nusret Kose; Ricardo F Pinero; Marden E Alder; Hoa L Duong; Jennifer L Surber
Journal:  J Bone Joint Surg Am       Date:  2003-03       Impact factor: 5.284

4.  Natural history of congenital kyphosis and kyphoscoliosis. A study of one hundred and twelve patients.

Authors:  M J McMaster; H Singh
Journal:  J Bone Joint Surg Am       Date:  1999-10       Impact factor: 5.284

5.  Early onset scoliosis: a call for awareness.

Authors:  A N Conner
Journal:  Br Med J (Clin Res Ed)       Date:  1984-10-13

6.  The vertical expandable prosthetic titanium rib implant for the treatment of thoracic insufficiency syndrome associated with congenital and neuromuscular scoliosis in young children.

Authors:  Anna K Hell; Robert M Campbell; Fritz Hefti
Journal:  J Pediatr Orthop B       Date:  2005-07       Impact factor: 1.041

7.  Results of surgical treatment for kyphotic deformity of the spine secondary to trauma or Scheuermann's disease.

Authors:  Teoman Atici; Ufuk Aydinli; Burak Akesen; Rasim Serifoğlu
Journal:  Acta Orthop Belg       Date:  2004-08       Impact factor: 0.500

8.  The effect of opening wedge thoracostomy on thoracic insufficiency syndrome associated with fused ribs and congenital scoliosis.

Authors:  Robert M Campbell; Melvin D Smith; Thomas C Mayes; John A Mangos; Donna B Willey-Courand; Nusret Kose; Ricardo F Pinero; Marden E Alder; Hoa L Duong; Jennifer L Surber
Journal:  J Bone Joint Surg Am       Date:  2004-08       Impact factor: 5.284

9.  An analysis of sagittal curves and balance after Cotrel-Dubousset instrumentation for kyphosis secondary to Scheuermann's disease. A review of 32 patients.

Authors:  T G Lowe; M D Kasten
Journal:  Spine (Phila Pa 1976)       Date:  1994-08-01       Impact factor: 3.468

10.  The usefulness of VEPTR in the older child with complex spine and chest deformity.

Authors:  Amer F Samdani; Tricia St Hilaire; John B Emans; John T Smith; Kit Song; Robert J Campbell; Randal R Betz
Journal:  Clin Orthop Relat Res       Date:  2009-05-20       Impact factor: 4.176

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  7 in total

1.  H3S2 (3 hooks, 2 screws) construct: a simple growing rod technique for early onset scoliosis.

Authors:  Lotfi Miladi; Alexandre Journe; Maryline Mousny
Journal:  Eur Spine J       Date:  2012-05-30       Impact factor: 3.134

2.  Bacterial colonization of VEPTR implants under repeated expansions in children with severe early onset spinal deformities.

Authors:  Christian Plaass; Carol Claudius Hasler; Ulrich Heininger; Daniel Studer
Journal:  Eur Spine J       Date:  2015-05-15       Impact factor: 3.134

3.  Early onset scoliosis: current concepts and controversies.

Authors:  Nicholas D Fletcher; Robert W Bruce
Journal:  Curr Rev Musculoskelet Med       Date:  2012-06

4.  A novel technique for treatment of progressive scoliosis in young children using a 3-hook and 2-screw construct (H3S2) on a single sub-muscular growing rod: surgical technique.

Authors:  Lotfi Miladi; Maryline Mousny
Journal:  Eur Spine J       Date:  2014-05-09       Impact factor: 3.134

5.  The Classification for Early-onset Scoliosis (C-EOS) Correlates With the Speed of Vertical Expandable Prosthetic Titanium Rib (VEPTR) Proximal Anchor Failure.

Authors:  Howard Y Park; Hiroko Matsumoto; Nicholas Feinberg; David P Roye; Wajdi W Kanj; Randal R Betz; Patrick J Cahill; Michael P Glotzbecker; Scott J Luhmann; Sumeet Garg; Jeffrey R Sawyer; John T Smith; John M Flynn; Michael G Vitale
Journal:  J Pediatr Orthop       Date:  2017-09       Impact factor: 2.324

Review 6.  Treatment of congenital thoracic scoliosis with associated rib fusions using VEPTR expansion thoracostomy: a surgical technique.

Authors:  Romain Dayer; Dimitri Ceroni; Pierre Lascombes
Journal:  Eur Spine J       Date:  2014-05-14       Impact factor: 3.134

7.  Extraspinal ossifications after implantation of vertical expandable prosthetic titanium ribs (VEPTRs).

Authors:  Vanja Zivkovic; Philippe Büchler; Dror Ovadia; Rolf Riise; Ralf Stuecker; Carol Hasler
Journal:  J Child Orthop       Date:  2014-04-22       Impact factor: 1.548

  7 in total

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