| Literature DB >> 21115212 |
Yu Luo1, Feng Xiao, Shijing Qian, Wei Lu, Bo Yang.
Abstract
A novel kind of thiazolylbenzimidazole derivatives were designed and synthesized and evaluated for their antitumor activity against SMMC-7721 and A549 cell lines. Most compounds showed good antitumor activities, and compound 11b displayed remarkable in vitro anticancer activity comparable to taxol. The preliminary structure-activity relationship of these benzimidazole derivatives was discussed based on the experimental data obtained.Entities:
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Year: 2010 PMID： 21115212 DOI： 10.1016/j.ejmech.2010.11.014
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514