INTRODUCTION: Karyotyping is often performed in transsexual individuals. AIM: Quantification and characterization of karyotype findings and abnormalities in transsexual persons. MAIN OUTCOME MEASURES: Karyotypes were listed both in male-to-female and in female-to-male transsexual persons. METHODS: The data were collected through a retrospective study. RESULTS: Karyotypes of 368 transsexual individuals (251 male-to-female, 117 female-to-male) are described. Normal findings were found in 97.55%. Prevalence of abnormal karyotypes was 3.19% among male-to-female, and 0.85% among female-to-male transsexuals. Nine karyotypes showed variations; Klinefelter syndrome was confirmed in three persons, whereas others displayed autosomal aberrations. CONCLUSION: Karyotyping is only of very limited information in the transsexual population.
INTRODUCTION: Karyotyping is often performed in transsexual individuals. AIM: Quantification and characterization of karyotype findings and abnormalities in transsexual persons. MAIN OUTCOME MEASURES: Karyotypes were listed both in male-to-female and in female-to-male transsexual persons. METHODS: The data were collected through a retrospective study. RESULTS: Karyotypes of 368 transsexual individuals (251 male-to-female, 117 female-to-male) are described. Normal findings were found in 97.55%. Prevalence of abnormal karyotypes was 3.19% among male-to-female, and 0.85% among female-to-male transsexuals. Nine karyotypes showed variations; Klinefelter syndrome was confirmed in three persons, whereas others displayed autosomal aberrations. CONCLUSION: Karyotyping is only of very limited information in the transsexual population.
Authors: Tatjana Sajevets; Charlotte Verroken; Gunter Heylens; Elfride De Baere; Guy T'Sjoen Journal: Asian J Androl Date: 2015 Sep-Oct Impact factor: 3.285
Authors: Matthias K Auer; Nina Höhne; María Ángeles Bazarra-Castro; Hildegard Pfister; Johannes Fuss; Günter K Stalla; Caroline Sievers; Marcus Ising Journal: PLoS One Date: 2013-10-23 Impact factor: 3.240