Franz F Wagner1. 1. DRK-Blutspendedienst NSTOB, Zentralinstitut Springe, Germany.
Abstract
SCREENING BLOOD DONORS FOR RARE ANTIGEN CONSTELLATIONS HAS BEEN IMPLEMENTED USING SIMPLE PCR METHODS: PCR with enzyme digestion has been used to type donor cohorts for Dombrock antigens, and PCR with sequence-specific priming to identify donors negative for antigens of high frequency. The advantages and disadvantages of the methods as well as their current state is discussed.
SCREENING BLOOD DONORS FOR RARE ANTIGEN CONSTELLATIONS HAS BEEN IMPLEMENTED USING SIMPLE PCR METHODS: PCR with enzyme digestion has been used to type donor cohorts for Dombrock antigens, and PCR with sequence-specific priming to identify donors negative for antigens of high frequency. The advantages and disadvantages of the methods as well as their current state is discussed.
Authors: Ghazala Hashmi; Tasmia Shariff; Yi Zhang; Joan Cristobal; Chiu Chau; Michael Seul; Prabhakar Vissavajjhala; Christopher Baldwin; Kim Hue-Roye; Dalisay Charles-Pierre; Christine Lomas-Francis; Marion E Reid Journal: Transfusion Date: 2007-04 Impact factor: 3.157
Authors: Franz F Wagner; Rita Bittner; Eduard K Petershofen; Andrea Doescher; Thomas H Müller Journal: Transfusion Date: 2008-04-15 Impact factor: 3.157