| Literature DB >> 21112523 |
Kazunari Karakida1, Takayuki Aoki, Haruo Sakamoto, Miho Takahashi, Tadashi Akamatsu, Go Ogura, Yasutomo Sekido, Yoshihide Ota.
Abstract
Malignant variants of ameloblastoma include metastasizing ameloblastoma, which microscopically appears benign but has metastasized and ameloblastic carcinoma that exhibits malignant histopathologic features. Ameloblastic carcinoma is classified into 2 types: a primary odontogenic malignancy and a secondary type resulting from malignant transformation of ameloblastoma. Most secondary ameloblastic carcinomas result from malignant transformation of a primary lesion after repeated postsurgical recurrences. Therefore it is rare to find an untreated secondary type presenting with histologic features of malignant transformation from an earlier benign lesion. We experienced a rare case of ameloblastic carcinoma, secondary type which might arise in an untreated ameloblastoma. The mechanism by which a preexisting benign ameloblastoma goes through a malignant transformation is also described. CrownEntities:
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Year: 2010 PMID： 21112523 DOI： 10.1016/j.tripleo.2010.08.018
Source DB: PubMed Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod ISSN： 1079-2104