Literature DB >> 21111034

Schisandrin B protects against solar irradiation-induced oxidative stress in rat skin tissue.

Philip Y Lam1, Chung Wai Yan, Po Yee Chiu, Hoi Yan Leung, Kam Ming Ko.   

Abstract

Schisandrin B (Sch B) and schisandrin C (Sch C), but not schisandrin A and dimethyl diphenyl bicarboxylate, protected rat skin tissue against solar irradiation-induced oxidative injury, as evidenced by a reversal of solar irradiation-induced changes in cellular reduced glutathione and α-tocopherol levels, as well as antioxidant enzyme activities and malondialdehyde production. The cytochrome P-450-mediated metabolism of Sch B or Sch C caused ROS production in rat skin microsomes. Taken together, Sch B or Sch C, by virtue of its pro-oxidant action and the subsequent eliciting of a glutathione antioxidant response, may prevent photo-aging of skin.
Copyright © 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID： 21111034     DOI： 10.1016/j.fitote.2010.11.018

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  6 in total

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Journal:  J Med Food       Date:  2014-07-14       Impact factor: 2.786

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Authors:  Eun-Jeong Kim; Minhee Jang; Min Jung Lee; Jong Hee Choi; Sung Joong Lee; Sun Kwang Kim; Dae Sik Jang; Ik-Hyun Cho
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Review 4.  Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives.

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Journal:  Nutrients       Date:  2019-02-04       Impact factor: 5.717

5.  Reducing oxidative stress may be important for treating pirarubicin-induced cardiotoxicity with schisandrin B.

Authors:  Heng Tang; Junhao Zhao; Rui Feng; Peng Pu; Li Wen
Journal:  Exp Ther Med       Date:  2021-11-23       Impact factor: 2.447

6.  Inhibitory and Acceleratory Effects of Inonotus obliquus on Tyrosinase Activity and Melanin Formation in B16 Melanoma Cells.

Authors:  Zheng-Fei Yan; Yang Yang; Feng-Hua Tian; Xin-Xin Mao; Yu Li; Chang-Tian Li
Journal:  Evid Based Complement Alternat Med       Date:  2014-08-13       Impact factor: 2.629
  6 in total

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