PURPOSE: To demonstrate that UVA/riboflavin crosslinking (CXL) can stop corneal melting in therapy resistant infectious corneal ulceration. METHODS: We will present a case report on a 70-year-old female patient referred for severe infectious ulcerative keratitis caused by Pseudomonas aeruginosa. After intensive treatment with fortified antibiotics, corneal melting developed. CXL was performed to avoid imminent corneal perforation. RESULTS: The CXL treatment was successful: the corneal melting was stopped and the lesion cicatrized, thereby avoiding emergency keratoplasty. CONCLUSION: This case report highlights that CXL may be a valuable addition to our therapeutic armamentarium in the treatment of corneal melts.
PURPOSE: To demonstrate that UVA/riboflavin crosslinking (CXL) can stop corneal melting in therapy resistant infectious corneal ulceration. METHODS: We will present a case report on a 70-year-old female patient referred for severe infectious ulcerative keratitis caused by Pseudomonas aeruginosa. After intensive treatment with fortified antibiotics, corneal melting developed. CXL was performed to avoid imminent corneal perforation. RESULTS: The CXL treatment was successful: the corneal melting was stopped and the lesion cicatrized, thereby avoiding emergency keratoplasty. CONCLUSION: This case report highlights that CXL may be a valuable addition to our therapeutic armamentarium in the treatment of corneal melts.
Authors: Natasha Babar; MiJung Kim; Kerry Cao; Yukari Shimizu; Su-Young Kim; Anna Takaoka; Stephen L Trokel; David C Paik Journal: Invest Ophthalmol Vis Sci Date: 2015-01-29 Impact factor: 4.799
Authors: Renata T Kashiwabuchi; Fabio R S Carvalho; Yasin A Khan; Flavio Hirai; Mauro S Campos; Peter J McDonnell Journal: Graefes Arch Clin Exp Ophthalmol Date: 2012-11-25 Impact factor: 3.117