Literature DB >> 21109703

Procedural sedation and analgesia in a large UK Emergency Department: factors associated with complications.

Keith G Jacques1, Alistair Dewar, Alasdair Gray, Dean Kerslake, Alexis Leal, Fiona Lees.   

Abstract

BACKGROUND: The aim of this study was to investigate the delivery of procedural sedation and analgesia (PSA) in an urban teaching hospital Emergency Department (ED) over a 2-year period, and identify factors associated with complications.
METHODS: Consecutive ED patients requiring PSA were prospectively enrolled onto the Registry of Emergency Procedural Sedation. Data collected included: patient and procedural characteristics; process times; physiological parameters; agents; sedation depth; and composition of staff team and complications. Multivariable binary logistic regression was used to identify factors associated with an increased risk of complications.
RESULTS: 1402 patents required PSA during the study period. 1345 (95.9%) underwent orthopaedic manipulations. 597 (42.6%) received moderate sedation. 401 (28.6%) were sedated to deeper levels. Complications occurred in 49 (3.5%) cases. Deeper levels of sedation and the procedure occurring overnight were identified as risk factors for complications. Procedure type, patient age, grade of doctor and choice of drug were not found to be associated with an increased risk of complications.
CONCLUSIONS: Procedural sedation and analgesia by Emergency Physicians is safe and effective; however, complications do happen. Complications are more likely at deeper levels of sedation and at night. Emergency Physicians must have the necessary skills and equipment to deal with such complications when they arise. EDs must be adequately staffed with trained clinicians 24 h a day to provide PSA.

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Mesh:

Year:  2010        PMID: 21109703     DOI: 10.1136/emj.2010.102475

Source DB:  PubMed          Journal:  Emerg Med J        ISSN: 1472-0205            Impact factor:   2.740


  7 in total

1.  Detection of respiratory compromise by acoustic monitoring, capnography, and brain function monitoring during monitored anesthesia care.

Authors:  Pedro P Tanaka; Maria Tanaka; David R Drover
Journal:  J Clin Monit Comput       Date:  2014-01-14       Impact factor: 2.502

2.  Procedural sedation in the emergency department by Dutch emergency physicians: a prospective multicentre observational study of 1711 adults.

Authors:  Gaël Jp Smits; Maybritt I Kuypers; Lisette Aa Mignot; Eef Pj Reijners; Erick Oskam; Karen Van Doorn; Wendy Amh Thijssen; Erik Hm Korsten
Journal:  Emerg Med J       Date:  2016-10-21       Impact factor: 2.740

3.  A study protocol for a feasibility study: Propofol Target-Controlled Infusion in Emergency Department Sedation (ProTEDS)-a multi-centre feasibility study protocol.

Authors:  Fiona M Burton; David J Lowe; Jonathan Millar; Alasdair R Corfield; Malcolm A B Sim
Journal:  Pilot Feasibility Stud       Date:  2019-02-18

4.  Propofol Target-Controlled Infusion in Emergency Department Sedation (ProTEDS): a multicentre, single-arm feasibility study.

Authors:  Fiona Marie Burton; David John Lowe; Jonathan Millar; Alasdair R Corfield; Malcolm J Watson; Malcolm A B Sim
Journal:  Emerg Med J       Date:  2020-12-09       Impact factor: 2.740

5.  Sedation-assisted Orthopedic Reduction in Emergency Medicine: The Safety and Success of a One Physician/One Nurse Model.

Authors:  David R Vinson; Casey L Hoehn
Journal:  West J Emerg Med       Date:  2013-02

6.  Adverse events and outcomes of procedural sedation and analgesia in major trauma patients.

Authors:  Robert S Green; Michael B Butler; Samuel G Campbell; Mete Erdogan
Journal:  J Emerg Trauma Shock       Date:  2015 Oct-Dec

Review 7.  Incidence of Adverse Events in Adults Undergoing Procedural Sedation in the Emergency Department: A Systematic Review and Meta-analysis.

Authors:  M Fernanda Bellolio; Waqas I Gilani; Patricia Barrionuevo; M Hassan Murad; Patricia J Erwin; Joel R Anderson; James R Miner; Erik P Hess
Journal:  Acad Emerg Med       Date:  2016-01-22       Impact factor: 3.451

  7 in total

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