| Literature DB >> 21109347 |
Suzane Ramos da Silva1, Ana Paula Ferraz da Silva, Maura Moscardi Bacchi, Carlos Eduardo Bacchi, Deilson Elgui de Oliveira.
Abstract
The present study aimed to evaluate the frequency of KSHV genotypes isolated from Kaposi sarcoma (KS) lesions in patients from Brazil. Fifty KS cases were evaluated. The most frequently detected viral genotypes were A (50.0%) and C (48.0%); the B genotype was isolated only in one case (2.0%). Noteworthy, there was a significant predominance of A genotypes in KS lesions from HIV-positive patients, whereas C genotypes were found mostly in the HIV-negative setting. This finding supports the hypothesis that distinct KSHV genotypes have a non-random distribution in KS, which might be attributable to unique biological properties. Copyright ÂEntities:
Mesh:
Year: 2010 PMID: 21109347 DOI: 10.1016/j.canlet.2010.10.011
Source DB: PubMed Journal: Cancer Lett ISSN: 0304-3835 Impact factor: 8.679