Literature DB >> 21109347

KSHV genotypes A and C are more frequent in Kaposi sarcoma lesions from Brazilian patients with and without HIV infection, respectively.

Suzane Ramos da Silva1, Ana Paula Ferraz da Silva, Maura Moscardi Bacchi, Carlos Eduardo Bacchi, Deilson Elgui de Oliveira.   

Abstract

The present study aimed to evaluate the frequency of KSHV genotypes isolated from Kaposi sarcoma (KS) lesions in patients from Brazil. Fifty KS cases were evaluated. The most frequently detected viral genotypes were A (50.0%) and C (48.0%); the B genotype was isolated only in one case (2.0%). Noteworthy, there was a significant predominance of A genotypes in KS lesions from HIV-positive patients, whereas C genotypes were found mostly in the HIV-negative setting. This finding supports the hypothesis that distinct KSHV genotypes have a non-random distribution in KS, which might be attributable to unique biological properties. Copyright Â
© 2010 Elsevier Ireland Ltd. All rights reserved.

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Year:  2010        PMID: 21109347     DOI: 10.1016/j.canlet.2010.10.011

Source DB:  PubMed          Journal:  Cancer Lett        ISSN: 0304-3835            Impact factor:   8.679


  5 in total

1.  Human herpesvirus 8 DNA detection and variant analysis in patients with multiple sclerosis.

Authors:  Sayed Mahdi Marashi; Aliehossadat Mostafa; Zabihollah Shoja; Ahmad Nejati; Shohreh Shahmahmoodi; Yaghoub Mollaei-Kandelous; Mohammad Ali Sahraian; Somayeh Jalilvand
Journal:  Virusdisease       Date:  2018-08-10

2.  Coupled transcriptome and proteome analysis of human lymphotropic tumor viruses: insights on the detection and discovery of viral genes.

Authors:  Lindsay R Dresang; Jeremy R Teuton; Huichen Feng; Jon M Jacobs; David G Camp; Samuel O Purvine; Marina A Gritsenko; Zhihua Li; Richard D Smith; Bill Sugden; Patrick S Moore; Yuan Chang
Journal:  BMC Genomics       Date:  2011-12-20       Impact factor: 3.969

3.  Genotypic distribution of HHV-8 in AIDS individuals without and with Kaposi sarcoma: Is genotype B associated with better prognosis of AIDS-KS?

Authors:  Tania Regina Tozetto-Mendoza; Karim Yaqub Ibrahim; Adriana Fumie Tateno; Cristina Mendes de Oliveira; Laura Massami Sumita; Maria Carmem Arroyo Sanchez; Expedito José Luna; Ligia Camara Pierrotti; Jan Felix Drexler; Paulo Henrique Braz-Silva; Claudio Sérgio Pannuti; Camila Malta Romano
Journal:  Medicine (Baltimore)       Date:  2016-11       Impact factor: 1.889

4.  K1 gene transformation activities in AIDS-related and classic type Kaposi's sarcoma: Correlation with clinical presentation.

Authors:  Ayumi Tamanaha-Nakasone; Karina Uehara; Yasuka Tanabe; Haruna Ishikawa; Natsuko Yamakawa; Zensei Toyoda; Kiyoto Kurima; Shinichiro Kina; Masayuki Tsuneki; Yuko Okubo; Sayaka Yamaguchi; Daisuke Utsumi; Kenzo Takahashi; Hirofumi Arakawa; Akira Arasaki; Takao Kinjo
Journal:  Sci Rep       Date:  2019-04-23       Impact factor: 4.379

5.  Case Report: Pulmonary Kaposi Sarcoma in a non-HIV patient.

Authors:  Arber Kodra; Maciej Walczyszyn; Craig Grossman; Daniel Zapata; Tarak Rambhatla; Bushra Mina
Journal:  F1000Res       Date:  2015-10-07
  5 in total

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