| Literature DB >> 21109313 |
Nayza Maciel de Britto Rosa1, Bárbara Zille de Queiroz, Daniele Sirineu Pereira, Mary Luci Avelar di Sabatino Santos, Daniela Matos Garcia Oliveira, Fabrícia Mendes E Silva Narciso, Leani Souza Máximo Pereira.
Abstract
Aging is related to a chronic increase in inflammatory cytokines. Adverse socioeconomic conditions are associated with increased plasma levels of these molecules, especially interleukin (IL)-6. Considering the differential profile of elderly Brazilians regarding their socioeconomic and cultural aspects, the objectives of this study were: to assess the correlation and differences between levels of IL-6 and socioeconomic status (education and income) in elderly women. IL-6 levels were measured using ELISA. The Spearman test was used to determine the correlation between IL-6 and socioeconomic status, and the Kruskal-Wallis and Mann-Whitney tests for cytokine level differences across education and income. IL-6 showed a significant inverse correlation with education (r = -0.205, p = 0.014) and income (r = -0.185, p = 0.028). Differences in IL-6 levels were registered across the education variables. The results corroborate evidence that low socioeconomic status is related to higher IL-6 plasma levels in elderly women.Entities:
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Year: 2010 PMID： 21109313 DOI： 10.1016/j.archger.2010.10.022
Source DB: PubMed Journal: Arch Gerontol Geriatr ISSN： 0167-4943 Impact factor: 3.250