Literature DB >> 21109186

Lipotoxicity and the development of heart failure: moving from mouse to man.

William C Stanley1, Fabio A Recchia.   

Abstract

Intracardiac lipid accumulation can cause heart failure. A study in Journal of Clinical Investigation (Son et al., 2010) found that cardiac-specific PPARγ overexpression caused heart failure with intracardiac triglyceride accumulation. Overexpressing PPARγ on a PPARα-/- background improved cardiac function, suggesting that specific lipid metabolites and lipid packaging determine cardiac lipotoxicity.
Copyright © 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID： 21109186      PMCID： PMC3330240          DOI： 10.1016/j.cmet.2010.11.016

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  9 in total

1.  Unmet potential for cardiovascular disease prevention in the United States.

Authors:  Rob M van Dam; Walter C Willett
Journal:  Circulation       Date:  2009-09-14       Impact factor: 29.690

2.  Too much or not enough of a good thing? Cardiac glucolipotoxicity versus lipoprotection.

Authors:  Heinrich Taegtmeyer; William C Stanley
Journal:  J Mol Cell Cardiol       Date:  2010-09-24       Impact factor: 5.000

Review 3.  Lipotoxic diseases.

Authors:  Roger H Unger
Journal:  Annu Rev Med       Date:  2002       Impact factor: 13.739

4.  PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation.

Authors:  Ni-Huiping Son; Shuiqing Yu; Joseph Tuinei; Kotaro Arai; Hiroko Hamai; Shunichi Homma; Gerald I Shulman; E Dale Abel; Ira J Goldberg
Journal:  J Clin Invest       Date:  2010-09-13       Impact factor: 14.808

Review 5.  Selected metabolic alterations in the ischemic heart and their contributions to arrhythmogenesis.

Authors:  P B Corr; K A Yamada
Journal:  Herz       Date:  1995-06       Impact factor: 1.443

Review 6.  Myocardial fatty acid metabolism in health and disease.

Authors:  Gary D Lopaschuk; John R Ussher; Clifford D L Folmes; Jagdip S Jaswal; William C Stanley
Journal:  Physiol Rev       Date:  2010-01       Impact factor: 37.312

Review 7.  Lipotoxicity: when tissues overeat.

Authors:  Jean E Schaffer
Journal:  Curr Opin Lipidol       Date:  2003-06       Impact factor: 4.776

Review 8.  Role of diet and fuel overabundance in the development and progression of heart failure.

Authors:  David J Chess; William C Stanley
Journal:  Cardiovasc Res       Date:  2008-03-14       Impact factor: 10.787

Review 9.  Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss.

Authors:  Carl J Lavie; Richard V Milani; Hector O Ventura
Journal:  J Am Coll Cardiol       Date:  2009-05-26       Impact factor: 24.094
  9 in total
  10 in total

Review 1.  Dietary fat and heart failure: moving from lipotoxicity to lipoprotection.

Authors:  William C Stanley; Erinne R Dabkowski; Rogerio F Ribeiro; Kelly A O'Connell
Journal:  Circ Res       Date:  2012-03-02       Impact factor: 17.367

Review 2.  Lipotoxicity and cardiac dysfunction in mammals and Drosophila.

Authors:  Ryan Tyge Birse; Rolf Bodmer
Journal:  Crit Rev Biochem Mol Biol       Date:  2011-08-19       Impact factor: 8.250

3.  Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy.

Authors:  Lalage A Katunga; Preeti Gudimella; Jimmy T Efird; Scott Abernathy; Taylor A Mattox; Cherese Beatty; Timothy M Darden; Kathleen A Thayne; Hazaim Alwair; Alan P Kypson; Jitka A Virag; Ethan J Anderson
Journal:  Mol Metab       Date:  2015-04-21       Impact factor: 7.422

Review 4.  Adiposopathy, "sick fat," Ockham's razor, and resolution of the obesity paradox.

Authors:  Harold Bays
Journal:  Curr Atheroscler Rep       Date:  2014-05       Impact factor: 5.113

5.  Prohibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure.

Authors:  Dechao Wu; Chongshu Jian; Qi Peng; Tingting Hou; Keling Wu; Bizhi Shang; Minglei Zhao; Yanru Wang; Wen Zheng; Qi Ma; Chuan-Yun Li; Heping Cheng; Xianhua Wang; Ling Zhao
Journal:  Cell Death Dis       Date:  2020-03-12       Impact factor: 8.469

6.  Progesterone receptor membrane component 1 reduces cardiac steatosis and lipotoxicity via activation of fatty acid oxidation and mitochondrial respiration.

Authors:  Sang R Lee; Jun H Heo; Seong Lae Jo; Globinna Kim; Su Jung Kim; Hyun Ju Yoo; Kyu-Pil Lee; Hyo-Jung Kwun; Hyun-Jin Shin; In-Jeoung Baek; Eui-Ju Hong
Journal:  Sci Rep       Date:  2021-04-22       Impact factor: 4.379

Review 7.  Gut Microbiota in Adipose Tissue Dysfunction Induced Cardiovascular Disease: Role as a Metabolic Organ.

Authors:  Xinyu Yang; Xianfeng Zhang; Wei Yang; Hang Yu; Qianyan He; Hui Xu; Shihui Li; Zi'ao Shang; Xiaodong Gao; Yan Wang; Qian Tong
Journal:  Front Endocrinol (Lausanne)       Date:  2021-09-06       Impact factor: 5.555

8.  MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet.

Authors:  Jun He; Megan T Quintana; Jenyth Sullivan; Traci L Parry; Trisha J Grevengoed; Jonathan C Schisler; Joseph A Hill; Cecelia C Yates; Rudo F Mapanga; M Faadiel Essop; William E Stansfield; James R Bain; Christopher B Newgard; Michael J Muehlbauer; Yipin Han; Brian A Clarke; Monte S Willis
Journal:  Cardiovasc Diabetol       Date:  2015-08-05       Impact factor: 9.951

9.  Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet.

Authors:  Megan T Quintana; Jun He; Jenyth Sullivan; Trisha Grevengoed; Jonathan Schisler; Yipin Han; Joseph A Hill; Cecelia C Yates; William E Stansfield; Rudo F Mapanga; M Faadiel Essop; Michael J Muehlbauer; Christopher B Newgard; James R Bain; Monte S Willis
Journal:  BMC Endocr Disord       Date:  2015-07-28       Impact factor: 2.763

10.  Distinct cardiac energy metabolism and oxidative stress adaptations between obese and non-obese type 2 diabetes mellitus.

Authors:  Xinghui Li; Yandi Wu; Jingjing Zhao; Haiping Wang; Jing Tan; Ming Yang; Yuanlong Li; Shijie Deng; Saifei Gao; Hui Li; Zhenyu Yang; Fengmin Yang; Jianxing Ma; Jianding Cheng; Weibin Cai
Journal:  Theranostics       Date:  2020-02-03       Impact factor: 11.556
  10 in total

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