Literature DB >> 2110863

Comparison of T suppressor factors from tumour-bearing mice and mice immunized with a monoclonal anti-idiotypic antibody.

J M Greer1, W J Halliday.   

Abstract

Certain dosage schedules of a monoclonal anti-idiotypic antibody (related to a murine bladder carcinoma) were found to induce suppressor factor production by syngeneic mice. This suppressor factor resembled the factor from tumour-bearing mice with respect to idiotype specificity, possession of molecular markers (reactive with anti-IJ and B16G antibodies) and production by Lyt2+IJ+ T cells in spleen cell cultures. The two factors differed with respect to Igh restriction in an in vitro assay (leucocyte adherence inhibition) and ability to suppress the induction of delayed-type hypersensitivity to tumour antigen.

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Year:  1990        PMID： 2110863     DOI： 10.1007/bf01744729

Source DB:  PubMed          Journal:  Cancer Immunol Immunother        ISSN： 0340-7004            Impact factor:   6.968


  24 in total

1.  Genetic and biological characterization of a T suppressor cell induced by anti-idiotypic antibody.

Authors:  J G Monroe; M Gurish; J Dambrauskas; M Slaoui; A Lowy; M I Greene
Journal:  J Immunol       Date:  1985-09       Impact factor: 5.422

2.  Tumor-specific idiotopes on suppressor factors and suppressor cells revealed by monoclonal anti-idiotope antibodies.

Authors:  V K Kuchroo; V K Lee; I Hellström; K E Hellström; W J Halliday
Journal:  Cell Immunol       Date:  1987-01       Impact factor: 4.868

3.  Delayed hypersensitivity to chemically induced tumors in mice and correlation with an in vitro test.

Authors:  W J Halliday; M Webb
Journal:  J Natl Cancer Inst       Date:  1969-07       Impact factor: 13.506

Review 4.  Genetics, expression, and function of idiotypes.

Authors:  K Rajewsky; T Takemori
Journal:  Annu Rev Immunol       Date:  1983       Impact factor: 28.527

5.  Specific anti-tumor responses of cultured immune spleen cells III. Further characterization of cells which synthesize factors with blocking and antiserum-dependent cellular cytotoxic (ADC) activities.

Authors:  K Nelson; S B Pollack; K E Hellström
Journal:  Int J Cancer       Date:  1975-10-15       Impact factor: 7.396

6.  T-T hybridoma product specifically suppresses tumor immunity.

Authors:  K Nelson; J Cory; I Hellström; K E Hellström
Journal:  Proc Natl Acad Sci U S A       Date:  1980-05       Impact factor: 11.205

7.  Monoclonal antiidiotypic antibodies related to a murine oncofetal bladder tumor antigen induce specific cell-mediated tumor immunity.

Authors:  V K Lee; T G Harriott; V K Kuchroo; W J Halliday; I Hellström; K E Hellström
Journal:  Proc Natl Acad Sci U S A       Date:  1985-09       Impact factor: 11.205

8.  Immunotherapy of murine sarcomas with auto-anti-idiotypic monoclonal antibodies which bind to tumor-specific T cells.

Authors:  K A Nelson; E George; C Swenson; J W Forstrom; K E Hellström
Journal:  J Immunol       Date:  1987-09-15       Impact factor: 5.422

9.  A two-chain tumour-related suppressor factor specific for a sequence antigen.

Authors:  T A Koppi-Reynolds; W J Halliday
Journal:  Immunol Lett       Date:  1984       Impact factor: 3.685

10.  Antigen- and receptor-driven regulatory mechanisms. I. Induction of suppressor T cells with anti-idiotypic antibodies.

Authors:  M S Sy; B A Bach; Y Dohi; A Nisonoff; B Benacerraf; M I Greene
Journal:  J Exp Med       Date:  1979-11-01       Impact factor: 14.307
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  1 in total

1.  Effects of anti-idiotype vaccine on tumour growth and on production of soluble factors modulating cell-mediated immunity in vitro.

Authors:  J M Greer; W J Halliday
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968
  1 in total

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