Literature DB >> 21107746

Neuroimmune pharmacology as a component of pharmacology in medical school curriculum.

Yuh F Chen1.   

Abstract

An introduction to the discipline of pharmacology is a standard part of the scientific foundation of medical school curricula. Neuroimmune pharmacology is a new subtopic that integrates fundamental concepts of neuroscience, immunology, infectious disease, and pharmacology. The integration of these areas is important to medical training in view of the growing concern over neurodegenerative diseases and cognitive disorders. This article introduces a submodule and concomitant syllabus for inclusion of neuroimmune pharmacology as a component of a pharmacology curriculum. The introductory lectures of neuroimmune pharmacology will concentrate on the role of the immune system in (1) schizophrenia and major depression; (2) neurodegenerative disorders; and (3) drug addiction. Emphasis will be placed on the competencies of critical thinking, problem solving, learning interest, and effectiveness of medical students. Problem-based learning and case study discussions will also be applied.

Entities:  

Mesh:

Year:  2010        PMID: 21107746     DOI: 10.1007/s11481-010-9252-5

Source DB:  PubMed          Journal:  J Neuroimmune Pharmacol        ISSN: 1557-1890            Impact factor:   4.147


  13 in total

Review 1.  Neurological basis of drug dependence and its effects on the immune system.

Authors:  Herman Friedman; Toby K Eisenstein
Journal:  J Neuroimmunol       Date:  2004-02       Impact factor: 3.478

2.  Modulation of the immune system in cannabis users.

Authors:  Roberta Pacifici; Piergiorgio Zuccaro; Simona Pichini; Pere N Roset; Sandra Poudevida; Magi Farré; Jordi Segura; Rafael De la Torre
Journal:  JAMA       Date:  2003-04-16       Impact factor: 56.272

Review 3.  Microbial infections, immunomodulation, and drugs of abuse.

Authors:  Herman Friedman; Catherine Newton; Thomas W Klein
Journal:  Clin Microbiol Rev       Date:  2003-04       Impact factor: 26.132

Review 4.  Elaborate interactions between the immune and nervous systems.

Authors:  Lawrence Steinman
Journal:  Nat Immunol       Date:  2004-06       Impact factor: 25.606

Review 5.  Neuroimmunopharmacologic effects of drugs of abuse.

Authors:  N R Hall; M P O'Grady; R A Menzies
Journal:  Adv Exp Med Biol       Date:  1991       Impact factor: 2.622

6.  Morphine impairs host innate immune response and increases susceptibility to Streptococcus pneumoniae lung infection.

Authors:  Jinghua Wang; Roderick A Barke; Richard Charboneau; Sabita Roy
Journal:  J Immunol       Date:  2005-01-01       Impact factor: 5.422

Review 7.  Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens.

Authors:  Esther M Sternberg
Journal:  Nat Rev Immunol       Date:  2006-04       Impact factor: 53.106

Review 8.  Bidirectional interaction between the central nervous system and the immune system.

Authors:  B S Rabin; S Cohen; R Ganguli; D T Lysle; J E Cunnick
Journal:  Crit Rev Immunol       Date:  1989       Impact factor: 2.214

Review 9.  The neurology of the immune system: neural reflexes regulate immunity.

Authors:  Mauricio Rosas-Ballina; Kevin J Tracey
Journal:  Neuron       Date:  2009-10-15       Impact factor: 17.173

Review 10.  Opiate abuse, innate immunity, and bacterial infectious diseases.

Authors:  Jinghua Wang; Roderick A Barke; Jing Ma; Richard Charboneau; Sabita Roy
Journal:  Arch Immunol Ther Exp (Warsz)       Date:  2008 Sep-Oct       Impact factor: 4.291

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