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Literature DB >> 21106550

Ascl2 and 11p15.5 amplification in colorectal cancer.

Adrian M Jubb, Klaus P Hoeflich, Peter M Haverty, Jennifer Wang, Hartmut Koeppen.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2010 PMID： 21106550 DOI： 10.1136/gut.2010.231746

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

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8 in total

1. R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells.

Authors: Jun Ye; Shanxi Liu; Yangyang Shang; Haoyuan Chen; Rongquan Wang
Journal: Cell Cycle Date: 2018-06-25 Impact factor: 4.534

2. Elevated ASCL2 expression in breast cancer is associated with the poor prognosis of patients.

Authors: Hui Xu; Xi-Long Zhao; Xue Liu; Xu-Gang Hu; Wen-Juan Fu; Qian Li; Yan Wang; Yi-Fang Ping; Xia Zhang; Xiu-Wu Bian; Xiao-Hong Yao
Journal: Am J Cancer Res Date: 2017-04-01 Impact factor: 6.166

3. MicroRNA-200 (miR-200) cluster regulation by achaete scute-like 2 (Ascl2): impact on the epithelial-mesenchymal transition in colon cancer cells.

Authors: Yin Tian; Qiong Pan; Yangyang Shang; Rong Zhu; Jun Ye; Yun Liu; Xiaoli Zhong; Shanshan Li; Yonghong He; Lei Chen; Jingjing Zhao; Wensheng Chen; Zhihong Peng; Rongquan Wang
Journal: J Biol Chem Date: 2014-11-04 Impact factor: 5.157

Ascl2 and 11p15.5 amplification in colorectal cancer.

1. R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells.

2. Elevated ASCL2 expression in breast cancer is associated with the poor prognosis of patients.

3. MicroRNA-200 (miR-200) cluster regulation by achaete scute-like 2 (Ascl2): impact on the epithelial-mesenchymal transition in colon cancer cells.

4. Elevated ASCL2 expression is associated with metastasis of osteosarcoma and predicts poor prognosis of the patients.

5. Small cell lung cancer tumors and preclinical models display heterogeneity of neuroendocrine phenotypes.

6. Comprehensive molecular characterization of human colon and rectal cancer.

7. Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.

8. Achaete scute-like 2 suppresses CDX2 expression and inhibits intestinal neoplastic epithelial cell differentiation.