Literature DB >> 21105033

A stabilizing influence: CAL PDZ inhibition extends the half-life of ΔF508-CFTR.

Patrick R Cushing1, Lars Vouilleme, Maria Pellegrini, Prisca Boisguerin, Dean R Madden.   

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Year:  2010        PMID： 21105033      PMCID： PMC3033200          DOI： 10.1002/anie.201005585

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  30 in total

1.  Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis.

Authors:  S H Cheng; R J Gregory; J Marshall; S Paul; D W Souza; G A White; C R O'Riordan; A E Smith
Journal:  Cell       Date:  1990-11-16       Impact factor: 41.582

Review 2.  The cystic fibrosis transmembrane conductance regulator.

Authors:  J R Riordan
Journal:  Annu Rev Physiol       Date:  1993       Impact factor: 19.318

3.  Altered chloride ion channel kinetics associated with the delta F508 cystic fibrosis mutation.

Authors:  W Dalemans; P Barbry; G Champigny; S Jallat; K Dott; D Dreyer; R G Crystal; A Pavirani; J P Lecocq; M Lazdunski
Journal:  Nature       Date:  1991 Dec 19-26       Impact factor: 49.962

4.  Identification of the cystic fibrosis gene: genetic analysis.

Authors:  B Kerem; J M Rommens; J A Buchanan; D Markiewicz; T K Cox; A Chakravarti; M Buchwald; L C Tsui
Journal:  Science       Date:  1989-09-08       Impact factor: 47.728

5.  Isolation of CF cell lines corrected at DeltaF508-CFTR locus by SFHR-mediated targeting.

Authors:  E Bruscia; F Sangiuolo; P Sinibaldi; K K Goncz; G Novelli; D C Gruenert
Journal:  Gene Ther       Date:  2002-06       Impact factor: 5.250

6.  E3KARP mediates the association of ezrin and protein kinase A with the cystic fibrosis transmembrane conductance regulator in airway cells.

Authors:  F Sun; M J Hug; C M Lewarchik; C H Yun; N A Bradbury; R A Frizzell
Journal:  J Biol Chem       Date:  2000-09-22       Impact factor: 5.157

Review 7.  Pharmacologic therapy for stop mutations: how much CFTR activity is enough?

Authors:  Eitan Kerem
Journal:  Curr Opin Pulm Med       Date:  2004-11       Impact factor: 3.155

8.  Lack of acrosome formation in mice lacking a Golgi protein, GOPC.

Authors:  Ryoji Yao; Chizuru Ito; Yasuko Natsume; Yoshinobu Sugitani; Hitomi Yamanaka; Shoji Kuretake; Kaoru Yanagida; Akira Sato; Kiyotaka Toshimori; Tetsuo Noda
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-30       Impact factor: 11.205

9.  The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.

Authors:  G L Lukacs; X B Chang; C Bear; N Kartner; A Mohamed; J R Riordan; S Grinstein
Journal:  J Biol Chem       Date:  1993-10-15       Impact factor: 5.157

Review 10.  Lung infections associated with cystic fibrosis.

Authors:  Jeffrey B Lyczak; Carolyn L Cannon; Gerald B Pier
Journal:  Clin Microbiol Rev       Date:  2002-04       Impact factor: 26.132
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  39 in total

Review 1.  Emerging Themes in PDZ Domain Signaling: Structure, Function, and Inhibition.

Authors:  Xu Liu; Ernesto J Fuentes
Journal:  Int Rev Cell Mol Biol       Date:  2018-06-28       Impact factor: 6.813

2.  The CFTR trafficking mutation F508del inhibits the constitutive activity of SLC26A9.

Authors:  Carol A Bertrand; Shalini Mitra; Sanjay K Mishra; Xiaohui Wang; Yu Zhao; Joseph M Pilewski; Dean R Madden; Raymond A Frizzell
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2017-03-30       Impact factor: 5.464

3.  Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity.

Authors:  Ziqing Qian; Xiaohua Xu; Jeanine F Amacher; Dean R Madden; Estelle Cormet-Boyaka; Dehua Pei
Journal:  Angew Chem Int Ed Engl       Date:  2015-03-17       Impact factor: 15.336

4.  Computational Analysis of Energy Landscapes Reveals Dynamic Features That Contribute to Binding of Inhibitors to CFTR-Associated Ligand.

Authors:  Graham T Holt; Jonathan D Jou; Nicholas P Gill; Anna U Lowegard; Jeffrey W Martin; Dean R Madden; Bruce R Donald
Journal:  J Phys Chem B       Date:  2019-11-27       Impact factor: 2.991

5.  Disabled-2 protein facilitates assembly polypeptide-2-independent recruitment of cystic fibrosis transmembrane conductance regulator to endocytic vesicles in polarized human airway epithelial cells.

Authors:  Kristine M Cihil; Philipp Ellinger; Abigail Fellows; Donna Beer Stolz; Dean R Madden; Agnieszka Swiatecka-Urban
Journal:  J Biol Chem       Date:  2012-03-07       Impact factor: 5.157

6.  Hybrid organic-inorganic inhibitors of a PDZ interaction that regulates the endocytic fate of CFTR.

Authors:  Rituparna Kundu; Patrick R Cushing; Brian V Popp; Yu Zhao; Dean R Madden; Zachary T Ball
Journal:  Angew Chem Int Ed Engl       Date:  2012-06-14       Impact factor: 15.336

7.  Stereochemical preferences modulate affinity and selectivity among five PDZ domains that bind CFTR: comparative structural and sequence analyses.

Authors:  Jeanine F Amacher; Patrick R Cushing; Lionel Brooks; Prisca Boisguerin; Dean R Madden
Journal:  Structure       Date:  2013-11-07       Impact factor: 5.006

8.  Serum- and glucocorticoid-induced protein kinase 1 (SGK1) increases the cystic fibrosis transmembrane conductance regulator (CFTR) in airway epithelial cells by phosphorylating Shank2E protein.

Authors:  Katja Koeppen; Bonita A Coutermarsh; Dean R Madden; Bruce A Stanton
Journal:  J Biol Chem       Date:  2014-05-08       Impact factor: 5.157

Review 9.  From the endoplasmic reticulum to the plasma membrane: mechanisms of CFTR folding and trafficking.

Authors:  Carlos M Farinha; Sara Canato
Journal:  Cell Mol Life Sci       Date:  2016-10-03       Impact factor: 9.261

10.  Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop.

Authors:  Jeanine F Amacher; Patrick R Cushing; Christopher D Bahl; Tobias Beck; Dean R Madden
Journal:  J Biol Chem       Date:  2012-12-15       Impact factor: 5.157
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