| Literature DB >> 211045 |
A J Barrett, P Longhurst, P Sneath, J G Watson.
Abstract
This study was designed to investigate physiological factors that affect blood CFU-C numbers. Exercise was found to produce a fourfold rise in blood colony forming cells, and a twofold rise in cluster forming cells accompanied by a lymphocytosis. ACTH-induced stress caused a twofold rise in blood colony and cluster forming cells accompanied by a neutrophil leucocytosis. The results suggest that blood CFU-C exchange with a large marginal pool as well as a bone marrown pool. The procedures described could be exploited in the use of leukapheresed nucleated cells as a source of stem cells for bone marrow transplantation.Entities:
Mesh:
Substances:
Year: 1978 PMID: 211045
Source DB: PubMed Journal: Exp Hematol ISSN: 0301-472X Impact factor: 3.084