Literature DB >> 21103478

Probing the role of the bridging C509 between the [Fe4S4] cubane and the [Ni(p)Ni(d)] centre in the A-cluster of acetyl-coenzyme A synthase.

Yi Liu1, Xiaofei Zhu, Feng Wang, Tianlei Ying, Pingwei Li, Zhong-Xian Huang, Xiangshi Tan.   

Abstract

The A-cluster of acetyl-coenzyme A synthase consists of an [Fe(4)S(4)] cubane bridged to a [Ni(p)Ni(d)] centre via C509 cysteinate. The bridging cysteinate, which could be substituted by histidine imidazole, mediates "communication" between the [Fe(4)S(4)] cubane and the [Ni(p)Ni(d)] centre during the synthesis of acetyl-coenzyme A.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 21103478     DOI: 10.1039/c0cc03587d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Functional Conversion of Acetyl-Coenzyme a Synthase to a Nickel Superoxide Dismutase via Rational Design of Coordination Microenvironment for the Nid-Site.

Authors:  Yaozhu Wei; Yajun Zhou; Hong Yuan; Yi Liu; Ying-Wu Lin; Jihu Su; Xiangshi Tan
Journal:  Int J Mol Sci       Date:  2022-02-28       Impact factor: 5.923

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.